Skip to main content
    • Aa
    • Aa

Readmission of known MRSA carriers and MRSA colonization pressure in hospital

  • P. GROHS (a1), B. PINEAU (a2), G. KAC (a3), L. GUTMANN (a1) (a4) and G. MEYER (a5) (a4)...

Readmission of asymptomatic methicillin-resistant Staphylococcus aureus (MRSA) carriers may contribute to the hospital reservoir. Using an electronic alert system, we assessed the weight of readmission of known MRSA carriers on MRSA colonization pressure in a hospital setting. During the 2004–2010 period, 2058 alerts were generated for 1060 inpatients. A total of 486/1060 patients (46%) were readmitted at least once, and 330/486 (64·4%) were readmitted <3 months after discharge. A mean of 20 MRSA patients were present on the same day (from 40 in 2004 to eight in 2010). The number of MRSA patient-days was 34 575, i.e. 2·5% of the 1 366 277 patient-days of the study period, and 17 737 (51·3%) MRSA patient-days were due to readmission of known MRSA carriers. The number of new MRSA cases was partly correlated with the number of MRSA patients hospitalized (R2 = 0·49). Rapid electronic identification of these patients proved essential in decreasing the global burden of MRSA in our hospital.

Corresponding author
*Author for correspondence: Mr P. Grohs, Department of Microbiology, AP-HP Hôpital Européen Georges Pompidou, 20-40 rue Leblanc, 75908 Paris Cedex 15, France. (Email:
Linked references
Hide All

This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

1. FD Lowy . Staphylococcus aureus infections. New England Journal of Medicine 1998; 339: 520532.

2. S Harbarth . Control of endemic methicillin-resistant Staphylococcus aureus – recent advances and future challenges. Clinical Microbiology and Infection 2006; 12: 11541162.

4. A Scanvic , Duration of colonization by methicillin-resistant Staphylococcus aureus after hospital discharge and risk factors for prolonged carriage. Clinical Infectious Disease 2001; 32: 13931398.

5. A Robicsek , JL Beaumont , LR Peterson . Duration of colonization with methicillin-resistant Staphylococcus aureus. Clinical Infectious Disease 2009; 48: 910913.

6. BS Cooper , Methicillin-resistant Staphylococcus aureus in hospitals and the community: stealth dynamics and control catastrophes. Proceedings of the National Academy of Sciences USA 2004; 101: 1022310228.

7. MM MacKinnon , KD Allen . Long-term MRSA carriage in hospital patients. Journal of Hospital Infection 2000; 46: 216221.

8. JV Robotham , Meticillin-resistant Staphylococcus aureus (MRSA) in hospitals and the community: model predictions based on the UK situation. Journal of Hospital Infection 2007; 65 (Suppl. 2): 9399.

11. D Pittet , Automatic alerts for methicillin-resistant Staphylococcus aureus surveillance and control: role of a hospital information system. Infection Control and Hospital Epidemiology 1996; 17: 496502.

12. G Kac , Impact of electronic alerts on isolation precautions for patients with multidrug-resistant bacteria. Archives of Internal Medicine 2007; 167: 20862090.

13.European Committee for Antimicrobial Susceptibility Testing (EUCAST) of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID). EUCAST Definitive Document E.DEF 2.1, August 2000: Determination of antimicrobial susceptibility test breakpoints. Clinical Microbiology and Infection 2000; 6: 570572.

14. KS Kaye , The deadly toll of invasive methicillin-resistant Staphylococcus aureus infection in community hospitals. Clinical Infectious Disease 2008; 46: 15681577.

Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Epidemiology & Infection
  • ISSN: 0950-2688
  • EISSN: 1469-4409
  • URL: /core/journals/epidemiology-and-infection
Please enter your name
Please enter a valid email address
Who would you like to send this to? *



Altmetric attention score

Full text views

Total number of HTML views: 2
Total number of PDF views: 4 *
Loading metrics...

Abstract views

Total abstract views: 88 *
Loading metrics...

* Views captured on Cambridge Core between September 2016 - 30th April 2017. This data will be updated every 24 hours.