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A review of the possible mechanisms for the persistence of foot-and-mouth disease virus

Published online by Cambridge University Press:  15 May 2009

E. L. Woodbury
World Reference Laboratory for FMD, Institute for Animal Health, Pirbright Laboratory, Ash Road, Pirbright, Surrey GU24 0NF, UK.
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Foot-and-mouth disease (FMD) was the first animal disease to be attributed to a virus, and the second virus to be discovered [1]. It is a positive-sense, singlestranded RNA picornavirus and the sole member of the genus Aphthovirus. Each infectious virus particle contains a single strand of RNA approximately 8-5 kb long. This is translated into a single polypeptide which is then cleaved into the structural and non-structural virus proteins.

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Copyright © Cambridge University Press 1995


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