Skip to main content
×
Home

Risk factors for indigenous Campylobacter jejuni and Campylobacter coli infections in The Netherlands: a case-control study

  • Y. DOORDUYN (a1), W. E. VAN DEN BRANDHOF (a1), Y. T. H. P. VAN DUYNHOVEN (a1), B. J. BREUKINK (a1), J. A. WAGENAAR (a2) (a3) (a4) and W. VAN PELT (a1)...
Summary
SUMMARY

A case-control study comprising 1315 Campylobacter jejuni cases, 121 Campylobacter coli cases and 3409 frequency-matched controls was conducted in The Netherlands in 2002–2003. Risk factors for both C. jejuni and C. coli enteritis were consumption of undercooked meat and barbecued meat, ownership of cats and use of proton pump inhibitors. Consumption of chicken was a predominant risk factor for C. jejuni enteritis, but many additional risk factors were identified. Unique risk factors for C. coli infections were consumption of game and tripe, and swimming. Contact with farm animals and persons with gastroenteritis were predominant risk factors for C. jejuni enteritis in young children (0–4 years). Important risk factors for the elderly (⩾60 years) were eating in a restaurant, use of proton pump inhibitors and having a chronic intestinal illness. Consumption of chicken in spring, steak tartare in autumn and winter and barbecued meat in rural areas showed strong associations with C. jejuni infections. This study illustrates that important differences in risk factors exist for different Campylobacter spp. and these may differ dependent on age, season or degree of urbanization.

Copyright
Corresponding author
*Author for correspondence: Y. Doorduyn, M.Sc., Epidemiology and Surveillance Unit, Netherlands Centre for Infectious Disease Control, National Institute of Public Health and the Environment, PO Box 1, 3720 BA, Bilthoven, The Netherlands. (Email: yvonne.doorduyn@rivm.nl)
References
Hide All
1.De Wit MA, et al. Sensor, a population-based cohort study on gastroenteritis in the Netherlands: incidence and etiology. American Journal of Epidemiology 2001; 154: 666674.
2.Mangen MJJ, et al. The costs of human Campylobacter infections and sequelae in the Netherlands: a DALY and cost-of-illness approach. Acta Agriculturae Scandinavica, Section C – Economy 2005; 2: 3551.
3.De Wit MA, et al. Gastroenteritis in sentinel general practices, The Netherlands. Emerging Infectious Diseases 2001; 7: 8291.
4.De Wit MA, et al. A comparison of gastroenteritis in a general practice-based study and a community-based study. Epidemiology and Infection 2001; 127: 389397.
5.Van Pelt W, et al. Laboratory surveillance of bacterial gastroenteric pathogens in The Netherlands, 1991–2001. Epidemiology and Infection 2003; 130: 431441.
6.Tam CC, et al. Incidence of Guillain-Barre syndrome among patients with Campylobacter infection: a general practice research database study. Journal of Infectious Diseases 2006; 194: 9597.
7.Hannu T, et al. Campylobacter-triggered reactive arthritis: a population-based study. Rheumatology (Oxford) 2002; 41: 312318.
8.Marshall JK, et al. Incidence and epidemiology of irritable bowel syndrome after a large waterborne outbreak of bacterial dysentery. Gastroenterology 2006; 131: 445450.
9.Haagsma JA, et al. Disease burden of post-infectious irritable bowel syndrome in The Netherlands. Epidemiology and Infection (in press).
10.Helms M, Simonsen J, Molbak K. Foodborne bacterial infection and hospitalization: a registry-based study. Clinical Infectious Diseases 2006; 42: 498506.
11.Cumberland P, et al. The infectious intestinal disease study of England: a prospective evaluation of symptoms and health care use after an acute episode. Epidemiology and Infection 2003; 130: 453460.
12.Karlinger K, et al. The epidemiology and the pathogenesis of inflammatory bowel disease. European Journal of Radiology 2000; 35: 154167.
13.Stafford RJ, et al. A multi-centre prospective case-control study of Campylobacter infection in persons aged 5 years and older in Australia. Epidemiology and Infection 2007; 135: 978988.
14.Friedman CR, et al. Risk factors for sporadic Campylobacter infection in the United States: a case-control study in FoodNet sites. Clinical Infectious Diseases 2004; 38: S285S296.
15.Neimann J, et al. A case-control study of risk factors for sporadic Campylobacter infections in Denmark. Epidemiology and Infection 2003; 130: 353366.
16.Neal KR, Slack RC. Diabetes mellitus, anti-secretory drugs and other risk factors for Campylobacter gastro-enteritis in adults: a case-control study. Epidemiology and Infection 1997; 119: 307311.
17.Danis K, et al. Risk factors for sporadic Campylobacter infection: an all-Ireland case-control study. Eurosurveillance 2009; 14.
18.Kapperud G, Espeland G, Wahl E, et al. Factors associated with increased and decreased risk of Campylobacter infection: a prospective case-control study in Norway. American Journal of Epidemiology 2003; 158: 234242.
19.Eberhart-Phillips J, et al. Campylobacteriosis in New Zealand: results of a case-control study. Journal of Epidemiology and Community Health 1997; 51: 686691.
20.Studahl A, Andersson Y. Risk factors for indigenous Campylobacter infection: a Swedish case-control study. Epidemiology and Infection 2000; 125: 269275.
21.Gallay A, et al. Risk factors for acquiring sporadic Campylobacter infection in France: results from a national case-control study. Journal of Infectious Diseases 2008; 197: 14771484.
22.Carrique-Mas J, et al. Risk factors for domestic sporadic campylobacteriosis among young children in Sweden. Scandinavian Journal of Infectious Diseases 2005; 37: 101110.
23.Tenkate TD, Stafford RJ. Risk factors for Campylobacter infection in infants and young children: a matched case-control study. Epidemiology and Infection 2001; 127: 399404.
24.Potter RC, Kaneene JB, Hall WN. Risk factors for sporadic Campylobacter jejuni infections in rural Michigan: a prospective case-control study. American Journal of Public Health 2003; 93: 21182123.
25.Gillespie IA, et al. A case-case comparison of Campylobacter coli and Campylobacter jejuni infection: a tool for generating hypotheses. Emerging Infectious Diseases 2002; 8: 937942.
26.Bouwknegt M, et al. Surveillance of zoonotic bacteria in farm animals in The Netherlands. Results from January 1998 until December 2000. Bilthoven: RIVM, 2003. Report No.: 285859013/2003.
27.Doorduyn Y, et al. Risk factors for Salmonella Enteritidis and Typhimurium (DT104 and non-DT104) infections in The Netherlands: predominant roles for raw eggs in Enteritidis and sandboxes in Typhimurium infections. Epidemiology and Infection 2006; 134: 617626.
28.Fermer C, Engvall EO. Specific PCR identification and differentiation of the thermophilic campylobacters, Campylobacter jejuni, C. coli, C. lari, and C. upsaliensis. Journal of Clinical Microbiology 1999; 37: 33703373.
29.Marshall SM, et al. Rapid identification of Campylobacter, Arcobacter, and Helicobacter isolates by PCR-restriction fragment length polymorphism analysis of the 16S rRNA gene. Journal of Clinical Microbiology 1999; 37: 41584160.
30.Rubin DB. Multiple Imputation for Nonresponse in Surveys. New York: Wiley, 1987.
31.Van de Giessen AW, et al. Surveillance of Salmonella spp. and Campylobacter spp. in poultry production flocks in The Netherlands. Epidemiology and Infection 2006; 134: 12661275.
32.Kivi M, Hofhuis A, Notermans DW, et al. A beef-associated outbreak of Salmonella Typhimurium DT104 in The Netherlands with implications for national and international policy. Epidemiology and Infection 2007; 135: 890899.
33.Doorduyn Y, et al. Shiga toxin-producing Escherichia coli (STEC) O157 outbreak, The Netherlands, September–October 2005. Eurosurveillance 2006; 11: 182185.
34.Greenland K, et al. Nationwide outbreak of STEC O157 infection in the Netherlands, December 2008–January 2009: continuous risk of consuming raw beef products. Eurosurveillance 2009; 14.
35.Ghafir Y, et al. A seven-year survey of Campylobacter contamination in meat at different production stages in Belgium. International Journal of Food Microbiology 2007; 116: 111120.
36.Wilson IG, Moore JE. Presence of Salmonella spp. and Campylobacter spp. in shellfish. Epidemiology and Infection 1996; 116: 147153.
37.Endtz HP, et al. Genotypic diversity of Campylobacter lari isolated from mussels and oysters in The Netherlands. International Journal of Food Microbiology 1997; 34: 7988.
38.Acke E, et al. Prevalence of thermophilic Campylobacter species in household cats and dogs in Ireland. Veterinary Record 2009; 164: 4447.
39.Bender JB, et al. Epidemiologic features of Campylobacter infection among cats in the upper midwestern United States. Journal of the American Veterinary Medical Association 2005; 226: 544547.
40.Hald B, Madsen M. Healthy puppies and kittens as carriers of Campylobacter spp., with special reference to Campylobacter upsaliensis. Journal of Clinical Microbiology 1997; 35: 33513352.
41.Ethelberg S, et al. Household outbreaks among culture-confirmed cases of bacterial gastrointestinal disease. American Journal of Epidemiology 2004; 159: 406412.
42.Sahin O, Kobalka P, Zhang Q. Detection and survival of Campylobacter in chicken eggs. Journal of Applied Microbiology 2003; 95: 10701079.
43.Harrington P, et al. Outbreak of Campylobacter jejuni infections associated with drinking unpasteurized milk procured through a cow-leasing program, Wisconsin, 2001. Morbidity and Mortality Weekly Reports 2002; 51: 548549.
44.Lehner A, et al. Epidemiologic application of pulsed-field gel electrophoresis to an outbreak of Campylobacter jejuni in an Austrian youth centre. Epidemiology and Infection 2000; 125: 1316.
45.Heuvelink AE, et al. Two outbreaks of campylobacteriosis associated with the consumption of raw cows' milk. International Journal of Food Microbiology 2009 (in press).
46.Teunis P, et al. A reconsideration of the Campylobacter dose-response relation. Epidemiology and Infection 2005; 133: 583592.
47.Ruiter H, et al. Campylobacter in water. A study of the presence of Campylobacter in swimming water and in possible emission sources [in Dutch]. Lelystad: Rijksinstituut voor Integraal Zoetwaterbeheer en Afvalwaterbehandeling, 2004. Report No.: 2004.005.
48.Havelaar AH, et al. Immunity to Campylobacter: its role in risk assessment and epidemiology. Critical Reviews in Microbiology (in press).
49.Belongia EA, et al. Diarrhea incidence and farm-related risk factors for Escherichia coli O157:H7 and Campylobacter jejuni antibodies among rural children. Journal of Infectious Diseases 2003; 187: 14601468.
50.Swift L, Hunter PR. What do negative associations between potential risk factors and illness in analytical epidemiological studies of infectious disease really mean? European Journal of Epidemiology 2004; 19: 219223.
Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Epidemiology & Infection
  • ISSN: 0950-2688
  • EISSN: 1469-4409
  • URL: /core/journals/epidemiology-and-infection
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×

Keywords:

Metrics

Altmetric attention score

Full text views

Total number of HTML views: 2
Total number of PDF views: 69 *
Loading metrics...

Abstract views

Total abstract views: 286 *
Loading metrics...

* Views captured on Cambridge Core between September 2016 - 19th November 2017. This data will be updated every 24 hours.