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The role of young children in a community-wide outbreak of hepatitis A

  • P. F. SMITH (a1) (a2), J. C. GRABAU (a1), A. WERZBERGER (a3), R. A. GUNN (a4), H. R. ROLKA (a4), S. F. KONDRACKI (a1), R. J. GALLO (a1) and D. L. MORSE (a1) (a2)...
    • Published online: 01 June 1997
Abstract

An Hasidic Jewish community has experienced recurrent hepatitis A outbreaks since 1980. To assess risk factors for illness during a 1985–6 outbreak, the authors reviewed case records and randomly selected 93 households for an interview and serologic survey. In the outbreak, 117 cases of hepatitis A were identified, with the highest attack rate (4·2%) among 3–5 year olds. Among the survey households, the presence of 3–5 year olds was the only risk factor that increased a household's risk of hepatitis A (indeterminant relative risk, P=0·02). Furthermore, case households from the outbreak were more likely to have 3–5 year olds than were control households from the survey (odds ratio=16·4, P<0·001). Children 3–5 years old were more likely to have hepatitis A and may have been the most frequent transmitters of hepatitis A in this community. Hepatitis A vaccination of 3–5 year olds can protect this age group and might prevent future outbreaks in this community.

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Corresponding author
All correspondence and requests for reprints: Division of Epidemiology; Room 503, Corning Tower, ESP; Albany, New York 12237-0608
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Epidemiology & Infection
  • ISSN: 0950-2688
  • EISSN: 1469-4409
  • URL: /core/journals/epidemiology-and-infection
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