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Serologic evidence of the postoperative persistence of hydatid cysts in man

Published online by Cambridge University Press:  15 May 2009

R. M. Matossian  and
G. F. Araj
R. M. Matossian
Affiliation:
Department of Bacteriology and Virology, American University of Beirut, Beirut, Lebanon
G. F. Araj
Affiliation:
Department of Bacteriology and Virology, American University of Beirut, Beirut, Lebanon
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Summary

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The sensitivity of the haemagglutination, complement-fixation and indirect fluorescent antibody tests in the diagnosis of primary and recurrent hydatid disease is presented. In the first, diagnostic titres were obtained in 90%, 80% and 96% of 50 patients with hepatic and 64%, 60% and 68% of 25 patients with pulmonary cysts, respectively. In the postoperative study of 62 patients, elevated titres of HA, CF and IFA antibodies in 30 led to the presumptive diagnosis of recurrent disease, confirmed later by radiological and surgical follow-ups. In the 32 others the proportion of positive reactors was 29%, 6% and 28% in HA, CF and IFA tests. These patients had no detectable cysts. This indicates that in post-operative patients a negative CF test may be of a better prognostic value in indicating absence of cysts than the HA and IFA tests.

Type
Research Article
Information
Journal of Hygiene , Volume 75 , Issue 3 , December 1975 , pp. 333 - 340
Copyright
Copyright © Cambridge University Press 1975

References

REFERENCES

Araj, G. F. (1973). Study of humoral antibodies in experimental hydatidosis of mice. MS. thesis, American University of Beirut, Beirut, Lebanon.Google Scholar
Botros, B. A. M., Moch, R. W. & Barsoum, I. S. (1973). Echinococcosis in Egypt: Evaluation of the indirect haemagglutination and latex agglutination tests for echinococcal serologic surveys. Journal of Tropical Medicine and Hygiene 76, 243.Google ScholarPubMed
Bradstreet, C. M. P. (1969). A study of two immunological tests in the diagnosis and prognosis of hydatid disease. Journal of Medical Microbiology 2, 419.CrossRefGoogle ScholarPubMed
Cohen, I. R., Norins, L. C. & Julian, A. J. (1967). Competition between, and effectiveness of IgG and IgM antibodies in indirect fluorescent antibody and other tests. Journal of Immunology 98, 143.CrossRefGoogle ScholarPubMed
Garabedian, G. A., Matossian, R. M. & Djanian, A. Y. (1957). An indirect hemagglutination test for hydatid disease. Journal of Immunology 78, 269.Google Scholar
Garabedian, G. A. (1971). Evaluation of the reactivity of hydatid whole scolex antigen in hydatid disease serology. Annals of Tropical Medicine and Parasitology 65, 385.CrossRefGoogle ScholarPubMed
Hariri, M. N., Schwabe, C. W. & Koussa, M. (1965). Host—parasite relationships in echinococcosis. XI. The antigen of the indirect hemagglutination test for hydatid disease. American Journal of Tropical Medicine and Hygiene 14, 592.Google Scholar
Huldt, G., Johansson, S. G. O. & Lantto, S. (1973). Echinococcosis in Northern Scandinavia. Immune reactions to Echinococcus granulosus in Kautokeino Lapps. Archives of Environmental Health 26, 36.Google Scholar
Kagan, I. G. (1968). A review of serological tests for the diagnosis of hydatid disease. Bulletin of the World Health Organization 39, 25.Google Scholar
Lass, N., Laver, Z. & Lengy, J. (1973). The immunodiagnosis of hydatid disease: Post-operative evaluation of the skin test and four serological tests. Annals of Allergy 31, 430.Google ScholarPubMed
Mamo, A. J. & Dakroub, R. (1974). A quick indirect hemagglutination test for the diagnosis of hydatid disease. Lebanese Medical Journal 27, 223.Google Scholar
Matossian, R. M. & Kane, G. J. (1971). The use of freeze dried erythrocytes as antigens in hydatid disease. Lebanese Medical Journal 24, 227.Google Scholar
Matossian, R. M., Kane, G. J., Chantler, S. M., Batty, I. & Sarhadian, H. (1972). The specific immunoglobulin in hydatid disease. Immunology 22, 423.Google Scholar
Mouton, R. P., Stoop, J. W., Ballieux, R. E. & Mul, N. A. J. (1970). Pneumococcal anti-bodies in IgA of serum and external secretions. Clinical and Experimental Immunology 7, 201.Google Scholar
Philip, R. N., Casper, E. A., Gordon, F. B. & Quan, A. L. (1974). Fluorescent antibody responses to chlamydial infection in patients with lymphogranuloma venereum and urethritis. Journal of Immunology 112, 2126.Google Scholar
Russi, S., Siracusano, A. & Vicari, G. (1974). Isolation and characterization of a blood P1 active carbohydrate antigen of Echinococcus granulosus cyst membrane. Journal of Immunology 112, 1061.CrossRefGoogle ScholarPubMed
Sever, L. I. (1962). Application of microtechnique to viral serological investigations. Journal of Immunology 88, 320.Google Scholar