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A space–time model for carbapenemase-producing Klebsiella pneumoniae (KPC) cluster quantification in a high-complexity hospital

  • C. S. ABBOUD (a1), J. MONTEIRO (a2), J. I. D. FRANÇA (a1), A. C. PIGNATARI (a3), E. E. DE SOUZA (a1), E. C. G. CAMARGO (a4), A. M. V. MONTEIRO (a4), R. G. DOS SANTOS (a3) and C. R. V. KIFFER (a3)...

A retrospective space–time permutation model with non-Euclidean distance criteria was applied within a high-complexity hospital setting to quantitatively explore cluster patterns of 273 patients infected with or colonized by carbapenemase-producing Klebsiella pneumoniae during 4 years. Results were compared to standard nosocomial active-surveillance methods. Two clusters were identified in the period, suggesting that space–time strategies for cluster quantification within confined environments may be useful.

Corresponding author
* Author for correspondence: C. R. V. Kiffer, Rua Leandro Dupret 188, Vila Clementino, São Paulo, Brazil, CEP 04025-010. (Email:
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Epidemiology & Infection
  • ISSN: 0950-2688
  • EISSN: 1469-4409
  • URL: /core/journals/epidemiology-and-infection
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