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A space–time model for carbapenemase-producing Klebsiella pneumoniae (KPC) cluster quantification in a high-complexity hospital

  • C. S. ABBOUD (a1), J. MONTEIRO (a2), J. I. D. FRANÇA (a1), A. C. PIGNATARI (a3), E. E. DE SOUZA (a1), E. C. G. CAMARGO (a4), A. M. V. MONTEIRO (a4), R. G. DOS SANTOS (a3) and C. R. V. KIFFER (a3)...
Summary

A retrospective space–time permutation model with non-Euclidean distance criteria was applied within a high-complexity hospital setting to quantitatively explore cluster patterns of 273 patients infected with or colonized by carbapenemase-producing Klebsiella pneumoniae during 4 years. Results were compared to standard nosocomial active-surveillance methods. Two clusters were identified in the period, suggesting that space–time strategies for cluster quantification within confined environments may be useful.

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Corresponding author
* Author for correspondence: C. R. V. Kiffer, Rua Leandro Dupret 188, Vila Clementino, São Paulo, Brazil, CEP 04025-010. (Email: carlos.rv.kiffer@gmail.com)
References
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1. Gupta, N, et al. Carbapenem resistant Enterobacteriaceae epidemiology and prevention. Clinical Infectious Diseases 2011; 53: 6067.
2. Abboud, CS, et al. First report of investigation into an outbreak due to carbapenemase-producing Klebsiella pneumoniae in a tertiary Brazilian hospital with extension to a patient in the community. Journal of Infection Prevention 2011; 12: 150153.
3. Nordmann, P, Cuzon, G, Naas, T. The real threat of Klebsiella pneumoniae carbapenemase producing bacteria. Lancet Infectious Diseases 2009; 9: 228236.
4. Clinical and Laboratory Standards Institute. Performance standards for antimicrobial susceptibility testing 22nd informational supplement. Clinical and Laboratory Standards Institute Document M100-S22, 2012. Wayne, PA, USA.
5. Anderson, KF, et al. Evaluation of methods to identify the Klebsiella pneumoniae carbapenemase in Enterobacteriaceae . Journal of Clinical Microbiology 2007; 45: 27232725.
6. Monteiro, J, et al. First report of KPC-2-producing Klebsiella pneumoniae strains in Brazil. Antimicrobial Agents and Chemotherapy 2009; 53: 333–4.
7. Kulldorff, M, et al. A space–time permutation scan statistic for the early detection of disease outbreaks. PLoS Medicine 2005; 2: 216224.
8. Gomez-Barroso, D, et al. Spatio-temporal analysis of tuberculosis in Spain, 2008–2010. International Journal of Tuberculosis and Lung Disease 2013; 17: 745–51.
9. Wang, LY, et al. Spatiotemporal patterns of Japanese encephalitis in China 2002–2010. PLoS Neglected Tropical Diseases 2013; 7: e2285, 18.
10. Ron, L, et al. Spatio-temporal clusters of incident human brucellosis cases in Ecuador. Spatial and Spatio-temporal Epidemiology 2013; 5:110.
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Epidemiology & Infection
  • ISSN: 0950-2688
  • EISSN: 1469-4409
  • URL: /core/journals/epidemiology-and-infection
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