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Spatial and temporal patterns in antimicrobial resistance of Salmonella Typhimurium in cattle in England and Wales

  • R. COX (a1) (a2), T. SU (a3), H. CLOUGH (a1), M. J. WOODWARD (a4) and C. SHERLOCK (a1) (a3)
  • DOI: http://dx.doi.org/10.1017/S0950268811002755
  • Published online: 03 January 2012
Abstract
SUMMARY

Salmonella is the second most commonly reported human foodborne pathogen in England and Wales, and antimicrobial-resistant strains of Salmonella are an increasing problem in both human and veterinary medicine. In this work we used a generalized linear spatial model to estimate the spatial and temporal patterns of antimicrobial resistance in Salmonella Typhimurium in England and Wales. Of the antimicrobials considered we found a common peak in the probability that an S. Typhimurium incident will show resistance to a given antimicrobial in late spring and in mid to late autumn; however, for one of the antimicrobials (streptomycin) there was a sharp drop, over the last 18 months of the period of investigation, in the probability of resistance. We also found a higher probability of resistance in North Wales which is consistent across the antimicrobials considered. This information contributes to our understanding of the epidemiology of antimicrobial resistance in Salmonella.

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Corresponding author
*Author for correspondence: Dr R. Cox, Centre for Veterinary Epidemiological Research, Atlantic Veterinary College, University of Prince Edward Island, Charlottetown, Prince Edward Island, Canada. (Email: rucox@upei.ca)
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Epidemiology & Infection
  • ISSN: 0950-2688
  • EISSN: 1469-4409
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