Skip to main content
×
Home
    • Aa
    • Aa
  • Get access
    Check if you have access via personal or institutional login
  • Cited by 6
  • Cited by
    This article has been cited by the following publications. This list is generated based on data provided by CrossRef.

    Chapelet, Guillaume Corvec, Stéphane Montassier, Emmanuel Herbreteau, Guillaume Berrut, Gilles Batard, Eric and de Decker, Laure 2016. Rapid detection of amoxicillin-susceptible Escherichia coli in fresh uncultured urine: a new tool to limit the use of broad-spectrum empirical therapy of community-acquired pyelonephritis. International Journal of Antimicrobial Agents, Vol. 47, Issue. 6, p. 486.


    Nomamiukor, Brenda O. Horner, Carolyne Kirby, Andrew and Hughes, Gareth J. 2015. Living conditions are associated with increased antibiotic resistance in community isolates ofEscherichia coli. Journal of Antimicrobial Chemotherapy, Vol. 70, Issue. 11, p. 3154.


    Martin, D. Fougnot, S. Grobost, F. Thibaut-Jovelin, S. Ballereau, F. Gueudet, T. de Mouy, D. and Robert, J. 2016. Prevalence of extended-spectrum beta-lactamase producing Escherichia coli in community-onset urinary tract infections in France in 2013. Journal of Infection, Vol. 72, Issue. 2, p. 201.


    Wang, Jann-Tay Chen, Pei-Chen Chang, Shan-Chwen Shiau, Yih-Ru Wang, Hui-Ying Lai, Jui-Fen Huang, I-Wen Tan, Mei-Chen and Lauderdale, Tsai-Ling Yang 2014. Antimicrobial susceptibilities of Proteus mirabilis: a longitudinal nationwide study from the Taiwan surveillance of antimicrobial resistance (TSAR) program. BMC Infectious Diseases, Vol. 14, Issue. 1,


    Medina-Polo, J. Guerrero-Ramos, F. Pérez-Cadavid, S. Arrébola-Pajares, A. Sopeña-Sutil, R. Benítez-Sala, R. Jiménez-Alcaide, E. García-González, L. Alonso-Isa, M. Lara-Isla, A. Passas-Martínez, J.B. and Tejido-Sánchez, Á. 2015. Community-associated urinary infections requiring hospitalization: Risk factors, microbiological characteristics and patterns of antibiotic resistance. Actas Urológicas Españolas (English Edition), Vol. 39, Issue. 2, p. 104.


    Medina-Polo, J. Guerrero-Ramos, F. Pérez-Cadavid, S. Arrébola-Pajares, A. Sopeña-Sutil, R. Benítez-Sala, R. Jiménez-Alcaide, E. García-González, L. Alonso-Isa, M. Lara-Isla, A. Passas-Martínez, J.B. and Tejido-Sánchez, Á. 2015. Infecciones urinarias adquiridas en la comunidad que requieren hospitalización: factores de riesgo, características microbiológicas y resistencia a antibióticos. Actas Urológicas Españolas, Vol. 39, Issue. 2, p. 104.


    ×

Surveillance of antibiotic susceptibility of Enterobacteriaceae isolated from urine samples collected from community patients in a large metropolitan area, 2010–2012

  • C. S. HORNER (a1) (a2), N. ABBERLEY (a1), M. DENTON (a1) (a2) and M. H. WILCOX (a1) (a2)
  • DOI: http://dx.doi.org/10.1017/S0950268813000988
  • Published online: 09 May 2013
Abstract
SUMMARY

Antibiotic susceptibilities of large cohorts of Enterobacteriaceae isolated from urine collected in the community are scarce. We report the susceptibilities of Enterobacteriaceae isolated from urine of non-selected community populations in a metropolitan area (Leeds and Bradford, UK) over 2 years. Isolates (n = 6614) were identified as follows: Escherichia coli (n = 5436), Klebsiella spp. (n = 525), Proteus mirabilis (n = 305), and 15 other species (n = 290); 58 isolates were unidentified. Ampicillin resistance was observed in 53% E. coli and 28% P. mirabilis; ⩾34% E. coli and P. mirabilis were non-susceptible to trimethoprim compared to 20% Klebsiella spp.; nitrofurantoin resistance was observed in 3% E. coli and 15% Klebsiella spp. The occurrence of extended-spectrum β-lactamases (ESBL) was low (6%), as was non-susceptibility to carbapenems, cefipime and tigecycline (<2%). Further surveillance is required to monitor this level of resistance and additional clinical studies are needed to understand the impact on the outcome of current empirical prescribing decisions.

Copyright
Corresponding author
*Author for correspondence: Dr C. S. Horner, Leeds Teaching Hospitals NHS Trust, Department of Microbiology, Old Medical School, Leeds General Infirmary, Leeds, UK. (Email: carolyne.horner@leedsth.nhs.uk)
Linked references
Hide All

This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

1.B Foxman . The epidemiology of urinary tract infection. Nature Reviews Urology 2010; 7: 653660.

2.N Woodford , Complete nucleotide sequences of plasmids pEK204, pEK499, and pEK516, encoding CTX-M enzymes in three major Escherichia coli lineages from the United Kingdom, all belonging to the international O25:H4-ST131 clone. Antimicrobial Agents and Chemotherapy 2009; 53: 44724482.

4.N Woodford , Community and hospital spread of Escherichia coli producing CTX-M extended-spectrum beta-lactamases in the UK. Journal of Antimicrobial Chemotherapy 2004; 54: 735743.

5.GM Rossolini , MM D'Andrea , C Mugnaioli . The spread of CTX-M-type extended-spectrum beta-lactamases. Clinical Microbiology and Infection 2008; 14 (Suppl. 1): 3341.

6.J Fernandez , Prevalence and risk factors of infections by multiresistant bacteria in cirrhosis: a prospective study. Hepatology 2012; 55: 15511561.

7.D Roux , Diversity of extended-spectrum beta-lactamase-producing Enterobacteriaceae on hospital admission. Scandinavian Journal of Infectious Diseases 2012; 44: 231236.

9.DM Livermore , Non-susceptibility trends among Enterobacteriaceae from bacteraemias in the UK and Ireland, 2001–06. Journal of Antimicrobial Chemotherapy 2008; 62 (Suppl. 2): ii41ii54.

11.DJ Farrell , A UK multicentre study of the antimicrobial susceptibility of bacterial pathogens causing urinary tract infection. Journal of Infection 2003; 46: 94100.

15.S Hillier , When do general practitioners request urine specimens for microbiology analysis? The applicability of antibiotic resistance surveillance based on routinely collected data. Journal of Antimicrobial Chemotherapy 2006; 58: 13031306.

Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Epidemiology & Infection
  • ISSN: 0950-2688
  • EISSN: 1469-4409
  • URL: /core/journals/epidemiology-and-infection
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×

Keywords:

Type Description Title
UNKNOWN
Supplementary Materials

Horner Supplementary Material
Figures S1-S3

 Unknown (50 KB)
50 KB