Skip to main content
    • Aa
    • Aa
  • Get access
    Check if you have access via personal or institutional login
  • Cited by 7
  • Cited by
    This article has been cited by the following publications. This list is generated based on data provided by CrossRef.

    Kaidarova, Zhanna Bravo, Marjorie D. Kamel, Hany T. Custer, Brian S. Busch, Michael P. and Lanteri, Marion C. 2016. Blood group A and D negativity are associated with symptomatic West Nile virus infection. Transfusion, Vol. 56, Issue. 7, p. 1699.

    Rujirojindakul, Pairaya Chongsuvivatwong, Virasakdi and Limprasert, Pornprot 2015. Association of ABO Blood Group Phenotype and Allele Frequency with Chikungunya Fever. Advances in Hematology, Vol. 2015, p. 1.

    Lao, T. T. Sahota, D. S. Chung, M.-K. Cheung, T. K. W. Cheng, Y. K. Y. and Leung, T. Y. 2014. Maternal ABO and rhesus blood group phenotypes and hepatitis B surface antigen carriage. Journal of Viral Hepatitis, Vol. 21, Issue. 11, p. 818.

    Pourhassan, Abolfazl 2014. Association Between ABO Blood/ Rhesus Grouping and Hepatitis B and C: A Case-control Study. Pakistan Journal of Biological Sciences, Vol. 17, Issue. 6, p. 868.

    Negri, Elaine Cristina Santarém, Vamilton Alvares Rubinsky-Elefant, Guita and Giuffrida, Rogério 2013. Anti-Toxocara spp. antibodies in an adult healthy population: serosurvey and risk factors in Southeast Brazil. Asian Pacific Journal of Tropical Biomedicine, Vol. 3, Issue. 3, p. 211.

    Sadeghian, Mohammad Hadi Keramati, Mohammad Reza Ayatollahi, Hossein Feizabadi, Atefeh Shirinzadeh Tehranaian, Farahnaz and Shakibyee, Hossein 2012. Is there any relationship between expressions of minor blood group antigens with HTLV-I infection?. Transfusion and Apheresis Science, Vol. 47, Issue. 2, p. 151.

    Wang, De-Shen Chen, Dong-Liang Ren, Chao Wang, Zhi-Qiang Qiu, Miao-Zhen Luo, Hui-Yan Zhang, Dong-Sheng Wang, Feng-Hua Li, Yu-Hong and Xu, Rui-Hua 2012. ABO blood group, hepatitis B viral infection and risk of pancreatic cancer. International Journal of Cancer, Vol. 131, Issue. 2, p. 461.


Variation in the host ABO blood group may be associated with susceptibility to hepatitis C virus infection

  • R. BEHAL (a1), R. JAIN (a2), K. K. BEHAL (a1) and T. N. DHOLE (a3)
  • DOI:
  • Published online: 14 December 2009

This study aimed to determine the relationship between hepatitis C virus (HCV) infection and ABO/Rhesus blood groups, age and sex. A total of 20 000 patients who came to donate blood in the blood bank of GSVM Medical College, Kanpur were enrolled in the study. Demographic data recorded for each patient included age, sex and blood group. Blood samples were tested for anti-HCV antibodies and ABO/Rhesus blood group antigen typing was performed. The overall positive rate of anti-HCV was 0·34%. We found that seropositivity for HCV increased with age. Anti-HCV antibodies were detected in 1/765 women (0·13%), compared to 67/19 235 men (0·35%). Seroprevalence of HCV was found to be higher in blood group O individuals (0·42%) and lowest in blood group AB individuals (0·04%). The results of this study demonstrate that that HCV infection may not be related to age and sex but the possible association of blood group antigens with HCV infection cannot be ruled out.

Corresponding author
*Author for correspondence: Professor T. N. Dhole, Department of Microbiology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Raibarelli Road, Lucknow, U.P., India226014. (Email:
Linked references
Hide All

This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

1.H Barth , TJ Liang , TF Baumert . Hepatitis C virus entry: molecular biology and clinical implications. Hepatology 2006; 44: 527535.

5.C Conry-Cantilena , Routes of infection, viremia and liver disease in blood donors found to have hepatitis C virus infection. New England Journal of Medicine 1996; 334: 16911696.

9.MR Lenka , E Ghosh , PK Bhattacharya . ABO and blood groups in relation to hepatitis B surface antigen. Transactions of the Royal Society of Tropical Medicine and Hygiene 1981; 75: 688.

11.A Poujol-Robert , Association between ABO blood group and fibrosis severity in chronic hepatitis C infection. Digestive Diseases and Sciences 2006; 51: 16331666.

13.G Garratty . Blood groups and disease: a historical perspective. Transfusion Medicine Reviews 2000; 14: 291301.

14.A Jain , The Prevalence of hepatitis C virus antibodies among the voluntary blood donors of New Delhi, India. European Journal of Epidemiology 2003; 18: 695697.

24.QL Choo , Genetic organization and diversity of the hepatitis C virus. Proceedings of the National Academy of Sciences USA 1991; 88: 24512455.

25.LH Miller , Erythrocyte receptors for Plasmodium knowlesi malaria: Duffy blood group determinants. Science 1975; 189: 561563.

26.LH Miller , The resistance factor to Plasmodium vivax in Blacks. New England Journal of Medicine 1976; 295: 302304.

29.M Kanbay , The relationship of ABO blood group, age, gender, smoking, and Helicobacter pylori infection. Digestive Diseases and Sciences 2005; 50: 12141217.

30.LF Paltanin , EM Reiche . Seroprevalence of anti-hepatitis C virus antibodies among blood donors, Brazil. Revista de Saúde Pública 2002; 36: 393399.

32.M Yano , Epidemiology and long term prognosis of hepatitis C virus infection in Japan. Gut 1993; 34: S13–16.

Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Epidemiology & Infection
  • ISSN: 0950-2688
  • EISSN: 1469-4409
  • URL: /core/journals/epidemiology-and-infection
Please enter your name
Please enter a valid email address
Who would you like to send this to? *