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Post-SSRI sexual dysfunction & other enduring sexual dysfunctions

  • David Healy (a1)

Abstract

Enduring sexual difficulties following treatment with selective serotonin reuptake inhibitor antidepressants have been reported to regulators since 1991, but it was only in 2006 that a formal post-SSRI sexual dysfunction syndrome was reported. The clinical, research and regulatory implications of this syndrome are considerable and researchers using epidemiological methods are well placed to map out the contours of the problem and perhaps pinpoint possible treatments.

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Copyright

This is an Open Access article, distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike licence (http://creativecommons.org/licenses/by-nc-sa/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the same Creative Commons licence is included and the original work is properly cited. The written permission of Cambridge University Press must be obtained for commercial re-use.

Corresponding author

Author for correspondence: David Healy, E-mail: David.Healy54@googlemail.com

References

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Bahrick, AS (2006) Post SSRI sexual dysfunction. American society for the advancement of pharmacotherapy. Tablet (brooklyn, New York, N Y ) 7, 23, 10–11.
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Healy, D, Le Noury, J and Mangin, D (2018 a) Citizen petition: sexual side effects of SSRIs and SNRIs. International Journal of Risk and Safety in Medicine 29, 125134.
Healy, D, Le Noury, J and Mangin, D (2018 b) Enduring sexual dysfunction after treatment with antidepressants, 5α-reductase inhibitors and isotretinoin: 300 cases. International Journal of Risk and Safety in Medicine 29, 135147.
Hogan, C, Le Noury, J, Healy, D and Mangin, D (2014) One hundred and twenty cases of enduring sexual dysfunction following treatment. International Journal of Risk and Safety in Medicine 26, 109116.
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Wang, GK, Mitchell, J and Wang, S-Y (2008) Block of persistent late Na+ currents by antidepressant sertraline and paroxetine. Journal of Membrane Biology 222, 7990.

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