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Renaming schizophrenia: 5 × 5

  • Sinan Guloksuz (a1) (a2) and Jim van Os (a1) (a3) (a4)


There had been a long way to go before we felt comfortable about even discussing the issues revolving around the concept of ‘schizophrenia’, let alone reckoning on mere semantic revision. In this editorial, we aim to extend our discussion on the reasons behind the slow death of the concept of ‘schizophrenia’ and the benefits of changing the name and embracing a spectrum approach with an umbrella psychosis spectrum disorder (PSD) category (similar to autism spectrum disorder) that goes further than a mere semantic revision. We attempted to cover the topic of the renaming by providing five most pertinent points categorised under five domains: reasons, signals, challenges, promises and steps for the change. Admittedly, even a modest revision, such as classifying all psychotic disorder categories under an umbrella category of PSD, and abolishing the term schizophrenia requires careful deliberation and some effort in the beginning, but the revision is well worth the effort considering the benefits in the long run. Renaming a particular form of mental suffering should be accompanied by a broader debate of the entire diagnosis-evidence-based-practice (EBP)-symptom-reduction model as the normative factor driving the content and organisation of mental health services that may be detached from patients’ needs and reality, overlooks the trans-syndromal structure of mental difficulties, appraises the significance of the technical features over the relational and ritual components of care, and underestimates the lack of EBP group-to-individual generalisability. Individuals may make great strides in attaining well-being by accommodating to living with mental vulnerabilities through building resilience in the social and existential domains. Changing the name and the concept of ‘schizophrenia’, which goes beyond a mere semantic revision, may become the first step that allows catalysation of the process of modernising psychiatric science and services worldwide.

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Corresponding author

Author for correspondence: Jim van Os, E-mail:


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Allardyce, J, Morrison, G, Van Os, J, Kelly, J, Murray, R and McCreadie, R (2000) Schizophrenia is not disappearing in south-west Scotland. The British Journal of Psychiatry 177, 3841.
Benoit, L, Moro, MR, Falissard, B and Henckes, N (2017) Psychosis risk research versus daily prognosis uncertainties: a qualitative study of French youth psychiatrists’ attitudes toward predictive practices. PLoS ONE 12, e0179849.
Carpenter, WT (2016) Shifting paradigms and the term schizophrenia. Schizophrenia Bulletin 42, 863864.
Chase, R (2008) Schizophrenia is a disease, so electrons aren't at risk. Nature 451, 127.
Cuthbert, BN and Insel, TR (2010) Toward new approaches to psychotic disorders: the NIMH Research Domain Criteria project. Schizophrenia Bulletin 36, 10611062.
George, B and Klijn, A (2013) A modern name for schizophrenia (PSS) would diminish self-stigma. Psychological Medicine 43, 15551557.
Gerson, M (2017) Trump's rhetorical schizophrenia is easy to see through. In The Washington Post.
Guloksuz, S and van Os, J (2018) The slow death of the concept of schizophrenia and the painful birth of the psychosis spectrum. Psychological Medicine 48, 229244.
Heckers, S, Barch, DM, Bustillo, J, Gaebel, W, Gur, R, Malaspina, D, Owen, MJ, Schultz, S, Tandon, R and Tsuang, M (2013) Structure of the psychotic disorders classification in DSM-5. Schizophrenia Research 150, 1114.
Henderson, S and Malhi, GS (2014) Swan song for schizophrenia? Australian & New Zealand Journal of Psychiatry 48, 302305.
Keshavan, MS, Nasrallah, HA and Tandon, R (2011) Schizophrenia, ‘Just the Facts’ 6. Moving ahead with the schizophrenia concept: from the elephant to the mouse. Schizophrenia Research 127, 313.
Keshavan, M, Tandon, R and Nasrallah, H (2013) Renaming schizophrenia: keeping up with the facts. Schizophrenia Research 148, 12.
Keshavan, MS, DeLisi, LE and Nasrallah, HA (2017) Translational and spectrum aspects of schizophrenia research: the rationale for new journal's new subheading. Schizophrenia Research 179, 1.
Kim, Y and Berrios, GE (2001) Impact of the term schizophrenia on the culture of ideograph: the Japanese experience. Schizophrenia Bulletin 27, 181185.
Koike, S, Yamaguchi, S, Ojio, Y, Ohta, K and Ando, S (2015) Effect of name change of schizophrenia on mass media between 1985 and 2013 in Japan: a text data mining analysis. Schizophrenia Bulletin 42, 552559.
Lasalvia, A, Penta, E, Sartorius, N and Henderson, S (2015) Should the label ‘schizophrenia’ be abandoned? Schizophrenia Research 162, 276284.
Levin, T (2006) Schizophrenia should be renamed to help educate patients and the public. International Journal of Social Psychiatry 52, 324331.
Lieberman, JA and First, MB (2007) Renaming schizophrenia. BMJ 334, 108.
Lieberman, JA and First, MB (2018) Psychotic disorders. New England Journal of Medicine 379, 270280.
Pitt, S (2016). It's a very ‘schizophrenic’ stock market, says this strategist – and here's why. In CNBC.
Robins, E and Guze, SB (1970) Establishment of diagnostic validity in psychiatric illness: its application to schizophrenia. American Journal of Psychiatry 126, 983987.
Sartorius, N, Chiu, H, Heok, KE, Lee, MS, Ouyang, WC, Sato, M, Yang, YK and Yu, X (2014) Name change for schizophrenia. Schizophrenia Bulletin 40, 255258.
Sato, M (2017) What have we learned from the name change for schizophrenia? Psychiatry and Clinical Neurosciences 71, 153153.
Schrieberg, D (2017) Pardon Me, Britain, Your Brexit Indecision Is Showing. In Forbes.
Takahashi, H, Ideno, T, Okubo, S, Matsui, H, Takemura, K, Matsuura, M, Kato, M and Okubo, Y (2009) Impact of changing the Japanese term for ‘schizophrenia’ for reasons of stereotypical beliefs of schizophrenia in Japanese youth. Schizophrenia Research 112, 149152.
van Os, J (2009) ‘Salience syndrome’ replaces ‘schizophrenia’ in DSM-V and ICD-11: psychiatry's evidence-based entry into the 21st century? Acta Psychiatrica Scandinavica 120, 363372.
van Os, J (2016) ‘Schizophrenia’ does not exist. BMJ 352, i375.
van Os, J, Guloksuz, S, Vijn, TW, Hafkenscheid, A and Delespaul, P (2018) The diagnosis-evidence-based group-level symptom-reduction model as the organizing principle for mental health care: time for change? World Psychiatry in press.
Yamaguchi, S, Mizuno, M, Ojio, Y, Sawada, U, Matsunaga, A, Ando, S and Koike, S (2017) Associations between renaming schizophrenia and stigma-related outcomes: a systematic review. Psychiatry and Clinical Neurosciences 71, 347362.



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