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OBSTETRIC ANTIPHOSPHOLIPID SYNDROME - A REVIEW

Published online by Cambridge University Press:  03 November 2011

K SCHREIBER
Affiliation:
St Thomas Hospital Lupus Research Unit, The Rayne Institute, King's College London School of Medicine, London, United Kingdom.
O ATEKA-BARRUTIA
Affiliation:
St Thomas Hospital Lupus Research Unit, The Rayne Institute, King's College London School of Medicine, London, United Kingdom.
MA KHAMASHTA*
Affiliation:
St Thomas Hospital Lupus Research Unit, The Rayne Institute, King's College London School of Medicine, London, United Kingdom.
GRV HUGHES
Affiliation:
St Thomas Hospital Lupus Research Unit, The Rayne Institute, King's College London School of Medicine, London, United Kingdom.
*
Munther A Khamashta, Lupus Research Unit, The Rayne Institute, St Thomas Hospital, London SE1 7EH, UK. E-mail address: munther.khamashta@kcl.ac.uk

Extract

The Antiphospholipid syndrome (APS) is one of the current hot topics embracing rheumatology and obstetrics.

The first clinical description of APS was in 1983. Venous or arterial thrombosis, abortion and cerebral manifestations along with circulating antibodies were the first described hallmarks of the syndrome. In the following years other clinical features, which include pregnancy complications, such as recurrent miscarriages (RM), pre-eclampsia or severe placental insufficiency were described.

Type
Review Article
Copyright
Copyright © Cambridge University Press 2011

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