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The genetic component in coronary heart disease – a review

Published online by Cambridge University Press:  14 April 2009

Forbes W. Robertson
Forbes W. Robertson
Affiliation:
Department of Genetics, University of Aberdeen, 2 Tillydrone Avenue, Aberdeen AB9 2TN
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The importance of atherosclerosis in public health has generated a vast literature relating to epidemiology of the disease, clinical descriptions of symptoms and records of variation of serum concentration of cholesterol, triglyceride or lipo-protein fractions in normal or affected persons. Such evidence has led to a number of hypotheses as to the origins of the disease, and although rival theories may be espoused with fervour or may fluctuate in popularity, a familial predisposition to coronary disease is a recurring theme. In this brief review, which does not aim to be exhaustive and is not concerned with hypertension, we shall focus attention on the more important aspects and attempt to set the conflicting evidence in perspective.

Information

Type
Research Article
Information
Genetics Research , Volume 37 , Issue 1 , February 1981 , pp. 1 - 16
Copyright
Copyright © Cambridge University Press 1981

References

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