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Genetics of lycopene cyclization and substrate transfer in β-carotene biosynthesis in Phycomyces

Published online by Cambridge University Press:  14 April 2009

S. Torres-Martínez ,
F. J. Murillo  and
E. Cerdá-Olmedo
S. Torres-Martínez
Affiliation:
Departamento de Genética, Facultad de Biología, Universidad de Sevilla, Sevilla, Spain
F. J. Murillo
Affiliation:
Departamento de Genética, Facultad de Biología, Universidad de Sevilla, Sevilla, Spain
E. Cerdá-Olmedo
Affiliation:
Departamento de Genética, Facultad de Biología, Universidad de Sevilla, Sevilla, Spain

Summary

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The mutations which block lycopene cyclization and those which stop substrate transfer along the carotene pathway are very closely linked in Phycomyces. Simultaneous blocking of both processes commonly results from single exposures to mutagens; and both blockings may be simultaneously removed after a second exposure. The frequencies of different kinds of mutants after treatments with the mutagens N-methyl-N′-nitro-N-nitrosoguanidine and ICR-170, their reversion patterns, and recombination analyses indicate that lycopene cyclization and substrate transfer are governed by separate segments of a single bifunctional gene.

Type
Research Article
Information
Genetics Research , Volume 36 , Issue 3 , December 1980 , pp. 299 - 309
Copyright
Copyright © Cambridge University Press 1980

References

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