Hostname: page-component-76fb5796d-9pm4c Total loading time: 0 Render date: 2024-04-29T10:48:39.546Z Has data issue: false hasContentIssue false
  • English
  • Français

High levels of fitness modifiers induced by hybrid dysgenesis in Drosophila melanogaster

Published online by Cambridge University Press:  14 April 2009

Benjamin J. Fitzpatrick  and
John A. Sved
Benjamin J. Fitzpatrick
Affiliation:
School of Biological Sciences, Sydney UniversityN.S.W. 2006, Australia
John A. Sved
Affiliation:
School of Biological Sciences, Sydney UniversityN.S.W. 2006, Australia
Rights & Permissions [Opens in a new window]

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Wild-type chromosomes of D. melanogaster mutagenized by passage through a single generation of hybrid dysgenesis have been compared against identical chromosomes passed through a reciprocal, non-dysgenic cross. Fitness of the chromosome in homozygous condition has been examined in population cages using the technique of balancer chromosome equilibration. The results indicate that amongst chromosomes with no lethal or visible mutation, more than 50% have suffered a measurable decline in fitness. The magnitude of this decline is estimated to be in the range 10–20%.

Type
Research Article
Information
Genetics Research , Volume 48 , Issue 2 , October 1986 , pp. 89 - 94
Copyright
Copyright © Cambridge University Press 1986

References

Bingham, P. M., Kidwell, M. G. & Rubin, G. M. (1982). The molecular basis of P-M hybrid dysgenesis: the role of the P element, a P strain-specific transposon family. Cell 25, 995–1004.CrossRefGoogle Scholar
Engels, W. R. (1979 a). Hybrid dysgenesis in Drosophila melanogaster: rules of inheritance of female sterility. Genetical Research 33, 219–236.CrossRefGoogle Scholar
Engels, W. R. (1979 b). Extrachromosomal control of mutability in Drosophila melanogaster. Proceedings of the National Academy of Science U.S.A. 76, 4011–4015.CrossRefGoogle ScholarPubMed
Haymer, D. S. & Hartl, D. L. (1982). The experimental assessment of fitness in Drosophila. I. Comparative measures of competitive reproductive success. Genetics 102, 455–466.CrossRefGoogle ScholarPubMed
Hiraizumi, Y. (1977). The relationships among transmission frequency, male recombination and progeny production in Drosophila melanogaster. Genetics 87, 83–93.Google Scholar
Kidwell, M. G., Kidwell, J. F. & Ives, P. T. (1977 a). Spontaneous non-reciprocal mutation and sterility in strain crosses of Drosophila melanogaster. Mutation Research 42, 89–98.CrossRefGoogle Scholar
Kidwell, M. G., Kidwell, J. F. & Sved, J. A. (1977 b). Hybrid dysgenesis in Drosophila melanogaster: a syndrome of aberrrant traits including mutation, sterility, and male recombination. Genetics 86, 813–833.CrossRefGoogle Scholar
Lewontin, R. C. (1974). The Genetic Basis of Evolutionary Change. New York: Columbia University Press.Google Scholar
Mackay, T. F. C. (1984). Jumping genes meet abdominal bristles: hybrid dysgenesis-induced quantitative variation in Drosophila melanogaster. Genetical Research 44, 231–237.CrossRefGoogle Scholar
Mackay, T. F. C. (1985). Transposable element-induced response to artificial selection in Drosophila melanogaster. Genetics 111, 351–374.CrossRefGoogle ScholarPubMed
Mackay, T. F. C. (1986). Transposable element-induced fitness mutations in Drosophila melanogaster. Genetical Research 48, 77–87.CrossRefGoogle Scholar
Mukai, T. (1964). The genetic structure of natural populations of Drosophila melanogaster. I. Spontaneous mutation rate of polygenes controlling viability. Genetics 50, 1–19.CrossRefGoogle ScholarPubMed
Mukai, T. & Cockerham, C. C. (1977). Spontaneous mutation rates at enzyme loci in Drosophila melanogaster. Proceedings of the National Academy of Science U.S.A. 74, 2514–2517.CrossRefGoogle ScholarPubMed
Pascoe, L. (1985). Fitness components of chromosomal homozygotes in Drosophila melanogaster age structured populations. PhD Thesis, University of Sydney.Google Scholar
Prout, T. (1965). The estimation of fitness from genotypic frequencies. Evolution 19, 546–551.Google Scholar
Rubin, G. M., Kidwell, M. G. & Bingham, P. M. (1982). The molecular basis of P-M hybrid dysgenesis: the nature of induced mutations. Cell 29, 987–994.CrossRefGoogle ScholarPubMed
Simmons, M. J. & Crow, J. F. (1977). Mutations affecting fitness in Drosophila populations. Annual Review of Genetics 11, 49–78.Google Scholar
Simmons, M. J. & Lim, J. K. (1980). Site specificity of mutations arising in dysgenic hybrids of Drosophila melanogaster. Proceedings of the National Academy of Sciences, U.S.A. 77, 6042–6046.CrossRefGoogle ScholarPubMed
Sved, J. A. (1971). An estimate of heterosis in Drosophila melanogaster. Genetical Research 18, 97–105.Google Scholar
Sved, J. A. & Ayala, F. J. (1970). A population cage test for heterosis in Drosophila pseudoobscura. Genetics 66, 97–113.CrossRefGoogle ScholarPubMed
Yukuhiro, K., Harada, K. & Mukai, T. (1985). Viability mutations induced by the P elements in Drosophila melanogaster. Japanese Journal of Genetics 60, 531–537.Google Scholar