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Multiple gene control of the tRNA aminoacylating system in Drosophila melanogaster*

Published online by Cambridge University Press:  14 April 2009

Raymond W. Rose  and
Ralph Hillman
Raymond W. Rose
Affiliation:
Biology Department, Temple University, Philadelphia, Pa., U.S.A.
Ralph Hillman
Affiliation:
Biology Department, Temple University, Philadelphia, Pa., U.S.A.
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Summary

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The stimulation of in vitro tRNA aminoacylation by post-microsomal supernatant enzymes isolated from Abnormal Abdomen (A53g) adult flies is a function of the residual genome of these flies rather than of the major mutant gene, A53g. Genes controlling this stimulation are located on the X chromosome as well as on the autosomes. These observations are discussed in terms of the phenotypic effect of the major mutant gene in response to changes in protein synthesis which are under the control of modifier genes responsible for aberrant genetic translation mechanisms.

Type
Research Article
Information
Genetics Research , Volume 21 , Issue 3 , June 1973 , pp. 239 - 245
Copyright
Copyright © Cambridge University Press 1973

References

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