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Multipoint maximum likelihood mapping in a full-sib family of an outbreeding species

  • J. W. VAN OOIJEN (a1)
  • DOI:
  • Published online: 31 August 2011

The fast multipoint maximum likelihood mapping algorithm for crosses between inbred lines, introduced by Jansen et al. (2001), is extended for mapping in a full-sib family of an outbreeding species. The method accommodates different segregation types of markers and differences in recombination between parents. The two separate parental multipoint maximum likelihood maps are joined into an integrated map by averaging lengths over anchored segments and by interpolating or extrapolating for markers segregating in one parent only. The method is illustrated with simulated data. The method will enable a more accurate estimation of maps in outbreeding species than current methods.

Corresponding author
*Corresponding author: Kyazma B.V., P. O. Box 182, 6700 AD Wageningen, the Netherlands. Email:
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D. Grattapaglia & R. Sederoff (1994). Genetic linkage maps of Eucalyptus grandis and Eucalyptus urophylla using a pseudo-testcross: mapping strategy and RAPD markers. Genetics 137, 11211137.

J. Jansen , A. G. De Jong & J. W. Van Ooijen (2001). Constructing dense genetic linkage maps. Theoretical and Applied Genetics 102, 11131122.

J. Jansen (2005). Construction of linkage maps in full-sib families of diploid outbreeding species by minimizing the number of recombinations in hidden inheritance vectors. Genetics 170, 20132025.

S. Kirkpatrick , C. D. Gelatt Jr & M. P. Vecchi (1983). Optimization by simulated annealing. Science 220, 671680.

E. S. Lander & P. Green (1987). Construction of multilocus genetic linkage maps in humans. Proceedings of the National Academy of Sciences USA 84, 23632367.

C. Maliepaard , J. Jansen & J. W. Van Ooijen (1997). Linkage analysis in a full-sib family of an outbreeding plant species: overview and consequences for applications. Genetical Research 70, 237250.

M. S. Ridout , S. Tong , C. J. Vowden & K. R. Tobutt (1998). Three-point linkage analysis in crosses of allogamous plant species. Genetical Research 72, 111121.

R. L. Wu , C. X. Ma , I. Painter & Z.-B. Zeng (2002 a). Simultaneous maximum likelihood estimation of linkage and linkage phases in outcrossing species. Theoretical Population Biology 61, 349363.

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