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Selection for recombination in a polygenic model

Published online by Cambridge University Press:  14 April 2009

J. Maynard Smith
Affiliation:
School of Biological Sciences, University of Sussex, Brighton BN1 9QG, U.K.
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Normalizing selection with a moving optimum can result in strong selection for increased recombination. This conclusion is based on computer simulation of an infinite, random-mating diploid population with additive, polygenic determination of the selected phenotype. There can also be selection for increased recombination with a fluctuating optimum, and with directional selection. These effects which arise in an infinite population appear to be large compared to the additional effects arising in a finite population because of the random generation of linkage disequilibrium.

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Type
Research Article
Copyright
Copyright © Cambridge University Press 1980