Ma N, et al.
Clinical and epidemiological charactersistics of individuals resistant to M. tuberculosis infection in a longitudinal TBHousehold contact study in Kampala, Uganda. BMC Infectious Diseases
2014; 14: 352.
Mycobacterium tuberculosis pathogenesis and molecular determinants of virulence. Clinical Microbiology Reviews
2003; 16: 463–496.
Van Crevel R, Ottenhoff THM, Van der Meer JWM.
Innate immunity to Mycobacterium tuberculosis
. Clinical Microbiology Reviews
2002; 15: 294–309.
Ernst JD, Trevejo-Nunez G, Banaiee N.
Genomics and the evolution, pathogenesis, and diagnosis of tuberculosis. The Journal of Clinical Investigation
2007; 117: 1738–1745.
Filliol I, et al.
Global phylogeny of Mycobacterium tuberculosis based on single nucleotide polymorphism (SNP) analysis: insights into tuberculosis evolution, phylogenetic accuracy of other DNA fingerprinting systems, and recommendations for a minimal standard SNP set. Journal of Bacteriology
2006; 188: 759–772.
Genetic epidemiology of tuberculosis susceptibility: impact of study design. PLoS Pathogens
2011; 7: e1001189.
Stein CM, et al.
Linkage and association analysis of candidate genes for TB and TNFalpha cytokine expression: evidence for association with IFNGR 1, IL-10, and TNF receptor 1 genes. Human Genetics
2007; 121: 663–673.
Tuberculosis 2004: challenges and opportunities. Transactions of the American Clinical and Climatological Association
2005; 116: 293–310.
Azad AK, Sadee W, Schlesinger LS.
Innate immune gene polymorphisms in tuberculosis. Infection and Immunity
2012; 80: 10.
Sirugo G, et al.
Genetic studies of African populations: an overview on disease susceptibility and response to vaccines and therapeutics. Human Genetics
2008; 123: 557–598.
Genomic insights into tuberculosis. Nature Rviews/Genetics
2014; 15: 307–317.
Marlo M, Eileen GH.
Current findings, challenges and novel approaches in human genetic susceptibility to tuberculosis. Tuberculosis
2010; 90: 71–83.
Aspects of genetic susceptibility to human infectious diseases. Annual Review of Genetics
2006; 40: 469–486.
Awomoyi AA, et al.
Interleukin-10, polymorphism in SLC11A1 (formerly NRAMP1), and susceptibility to tuberculosis. Journal of Infectious Diseases
2002; 186: 1808–1814.
Bellamy R, et al.
Variations in the NRAMP1 gene and susceptibility to tuberculosis in West Africans. New England Journal of Medicine
1998; 338: 640–644.
Awomoyi AA, et al.
Polymorphism in IL1B: IL1B-511 association with tuberculosis and decreased lipopolysaccharide-induced IL-1beta in IFN-gamma primed ex-vivo whole blood assay. Journal of Endotoxin Research
2005; 11: 281–286.
Bornman L, et al.
Vitamin D receptor polymorphisms and susceptibility to tuberculosis in West Africa: a case-control and family study. Journal of Infectious Diseases
2004; 190: 1631–1641.
Lombard Z, et al.
Association of HLA-DR, -DQ, and vitamin D receptor alleles and haplotypes with tuberculosis in the Venda of South Africa. Human Immunology
2006; 67: 643–654.
Olesen R, et al.
DC-SIGN (CD209), pentraxin 3 and vitamin D receptor gene variants associate with pulmonary tuberculosis risk in West Africans. Genes and Immunity
2007; 8: 456–467.
Li CM, et al.
Association of a polymorphism in the P2X7 gene with tuberculosis in a Gambian population. Journal of Infectious Diseases
2002; 186: 1458–1462.
Bellamy R, et al.
Genetic susceptibility to tuberculosis in Africans: a genome-wide scan. Proceedings of the National Academy of Sciences of the United States of America
2000; 97: 8005–8009.
Hall NB, et al.
Polymorphisms in TICAM2 and IL1B are associated with TB. Genes and Immunity
2015; 16: 127–133.
Malik S, et al.
Variants of the SFTPA1 and SFTPA2 genes and susceptibility to tuberculosis in Ethiopia. Human Genetics
2005; 118: 752–759.
Hiroyuki T, et al.
Synergistic effect of Nod1 and Nod2 agonists with Toll-Like receptor agonists on human dendritic cells to generate interleukin-12 and T helper type 1 cells. Infection and Immunity
2005; 73: 12.
Contribution of Toll-like receptors to innate immune responses to gram-negative and gram-positive bacteria. The American Journal of Hematology
2007; 109: 4.
Takeda K, Akir S.
Toll-like receptors in innate immunity. The Japaneees Society for Immunology
2005; 17: 1.
Seya T, et al.
TICAM-1 and TICAM-2: toll-like receptor adapters that participate in induction of type 1 interferons. International Journal of Biochemistry & Cell Biology
2005; 37: 3.
Yoshiaki E, et al.
Structures and interface mapping of the TIR domaincontaining adaptor molecules involved ininterferon signaling. Proceedings of the National Academy of Sciences
2013; 110: 49.
Magali M, et al.
Roles for Treg Expansion and HMGB1 Signaling through the TLR1-2-6 axis in determining the magnitude of the antigen-specific immune response to MVA85A. PLOS ONE
2013; 8: 7.
Lilian OM, Dario SZ.
NOD1 and NOD2 signaling in infection and inflamation. Frontiers in Immunology
2012; 3: 28.
Luigi F, et al.
Intracellular NOD-like receptors in innate immunity, infection and disease. Cellular Microbiology
2008; 10: 1.
Esmeralda J, et al.
Nucleotide-oligomerizing domain-1 (NOD1) receptor activation induces pro-inflammatory responses and autophagy in human alveolar macrophages. BMC Pulmonary Medicine
2014; 4: 152.
Jun-young L, et al.
The role of nucleotide-binding oligomerization domain 1 (NOD1) in cytokine production by macrophages in response to Mycobacterium tuberculosis
. In Conference: 2nd Annual Meeting of the International-Cytokine-and-Interferon – Society, 2014, vol. 70.
Pagani L, et al.
Ethiopian genetic diversity reveals linguistic stratification and complex influences on the Ethiopian gene pool. The American Journal of Human Genetics
2012; 91: 83–96.
Pagani L, et al.
Tracing the route of modern humans out of Africa by using 225 human genome sequences from Ethiopians and Egyptians. The American Journal of Human Genetics
2015; 96: 1–5.
Semino O, et al.
Ethiopians and Khoisan share the deepest clades of the human Y-chromosome phylogeny. American Journal of Human Genetics
2002; 70: 265–268.
Kivisild K, et al.
Ethiopian mitochondrial DNA heritage: tracking gene flow across and around the gate of tears. American Journal of Human Genetics
2004; 75: 752–770.
Lovell A, et al.
Ethiopia: between Sub-Saharan Africa and western Eurasia. Annals of Human Genetics
2005; 69: 275–287.
Liu H, et al.
A geographically explicit genetic model of worldwide human-settlement history. The American Journal of Human Genetics
2006; 79: 230–237.
Poloni ES, et al.
Genetic evidence for complexity in ethnic differentiation and history in East Africa. Annals of Human Genetics
2009; 73; 582–600.
Gurdasani D, et al.
The African genome variation project shapes medical genetics in Africa. Nature
2014; 517: 327–332.
Host-pathogen coevolution in human tuberculosis. Philosophical Transactions of the Royal Society of London B: Biological Sciences
2012; 367: 850–859.
Vermund S, Yamamoto N.
Co-infection with human immunodeficiency virus and tuberculosis in Asia. Tuberculosis (Edinb)
, 2007; 87: 18–25.
Nahid P, et al.
Treatment outcomes of patients with HIV and tuberculosis. American Journal of Respiratory and Critical Care Medicine
2007; 175: 11.
Rice JP, et al.
Definition of the Phenotype. Advances in Genetics. Academic Press; 2001, vol. 42.
Rebuma F, et al.
Mycobacterial lineages causing pulmonary and extrapulmonary tuberculosis, Ethiopia. Emerging Infectious Diseases
2013; 19: 3.
Yimer SA, et al.
Mycobacterium tuberculosis lineage 7 strains are associated with prolonged patient delay in seeking treatment for pulmonary tuberculosis in Amhara Region, Ethiopia. Journal of Clinical Microbiology, 2015; 53: 4.
Mulugeta B, et al.
Strain diversity of Mycobacterium tuberculosis isolates from pulmonary tuberculosis patients in afar pastoral region of Ethiopia. BioMed Research International
2014; 2014. doi: 10.1155/2014/238532.
Federal Ministry of Health of Health, Ethiopia. Tuberculosis, Leprosy and TB/HIV Prevention and Control Programme (Manual)
Federal Ministry of Health of Health, Ethiopia. Manual of the National Tuberculosis and Leprosy Control Program, Ethiopia. 1997.
Mengistu MM, Tesfaye WT, Madeley JR.
The quality of tuberculosis diagnosis in districts of Tigray region of northern Ethiopia. The Ethiopian Journal of Health Development
2005; 19: 13–20.
Beall CM, et al.
An Ethiopian pattern of human adaptation to high-altitude hypoxia. Proceedings of the National Academy of Sciences
2002; 99: 17215–17218.
H3Africa Consortium. Research capacity: enabling the genomic revolution in Africa. Science
2014; 344: 1346–1348.