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Clostridioides difficile infection following dental antibiotic prescriptions in a cohort of US veterans

Published online by Cambridge University Press:  21 February 2022

Geneva M. Wilson*
Affiliation:
Center of Innovation for Complex Chronic Healthcare (CINCCH), Hines Jr. Veterans’ Affairs Hospital, Hines, Illinois
Charlesnika T. Evans
Affiliation:
Center of Innovation for Complex Chronic Healthcare (CINCCH), Hines Jr. Veterans’ Affairs Hospital, Hines, Illinois Department of Preventive Medicine, Center for Health Services and Outcomes Research, Northwestern University Feinberg School of Medicine, Chicago, Illinois
Margaret A. Fitzpatrick
Affiliation:
Center of Innovation for Complex Chronic Healthcare (CINCCH), Hines Jr. Veterans’ Affairs Hospital, Hines, Illinois Division of Infectious Diseases, Department of Medicine, Loyola University Chicago Stritch School of Medicine, Maywood, Illinois
Linda Poggensee
Affiliation:
Center of Innovation for Complex Chronic Healthcare (CINCCH), Hines Jr. Veterans’ Affairs Hospital, Hines, Illinois
Gretchen Gibson
Affiliation:
VHA Office of Dentistry, Fayetteville, Arkansas
M. Marianne Jurasic
Affiliation:
VHA Office of Dentistry, Bedford, Massachusetts Departments of General Dentistry and Health Policy and Health Services Research, Boston University School of Dental Medicine, Boston, Massachusetts
Kelly Echevarria
Affiliation:
Antimicrobial Stewardship Task Force, Pharmacy Benefits Management Program, US Department of Veterans’ Affairs, Washington, District of Colombia
Katie J. Suda
Affiliation:
Center for Health Equity Research and Promotion, VA Pittsburgh Heath Care System, Pittsburgh, Pennsylvania Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania
*
Author for correspondence: Geneva Wilson, E-mail: geneva.wilson2@va.gov

Abstract

Among 108 (0.05% of cohort) US veterans with a Clostridioides difficile infection (CDI) within 30 days of a dental antibiotic prescription, 80% of patients received guideline-discordant antibiotics. Half had chronic gastrointestinal illness potentially exacerbating their CDI risk. More efforts are needed to improve antibiotic stewardship.

Type
Concise Communication
Copyright
© The Author(s), 2022. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America

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