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Diving deep for the needle in the haystack: An outbreak investigation of Burkholderia cenocepacia bacteremia

Published online by Cambridge University Press:  04 January 2024

Abdul Ghafur*
Affiliation:
Infectious Diseases, Apollo Cancer Institute, Teynampet, Chennai
Praveen Balaguru
Affiliation:
Infectious Diseases, Apollo Cancer Institute, Teynampet, Chennai
S. G. Ramanan
Affiliation:
Medical Oncology, Apollo Cancer Institute, Teynampet, Chennai
Rejiv Rajendranath
Affiliation:
Medical Oncology, Apollo Cancer Institute, Teynampet, Chennai
Revathi Raj
Affiliation:
Pediatric Hemato-Oncology, Apollo Cancer Institute, Teynampet, Chennai
Mohammed Zehran
Affiliation:
Medical Oncology, Apollo Cancer Institute, Teynampet, Chennai
T. Raja
Affiliation:
Medical Oncology, Apollo Cancer Institute, Teynampet, Chennai
Jose M. Easow
Affiliation:
Medical Oncology, Apollo Cancer Institute, Teynampet, Chennai
Sankar Srinivasan
Affiliation:
Medical Oncology, Apollo Cancer Institute, Teynampet, Chennai
Dedeepiya Devaprasad
Affiliation:
Critical Care, Apollo Cancer Institute, Teynampet, Chennai
Thilakavathy Sukumar
Affiliation:
Apollo Cancer Institute, Teynampet, Chennai
Praveen Nilgar
Affiliation:
Apollo Cancer Institute, Teynampet, Chennai
K. Sakthivel
Affiliation:
Pharmacy, Apollo Cancer Institute, Teynampet, Chennai
Rakkesh M. Nirumal
Affiliation:
Pharmacy, Apollo Cancer Institute, Teynampet, Chennai
K. Chandra
Affiliation:
Infection Control, Apollo Cancer Institute, Teynampet, Chennai
Sree V. Lakshmi
Affiliation:
Microbiology, Apollo Cancer Institute, Teynampet, Chennai
Nandini Sethuraman
Affiliation:
Microbiology, Apollo Hospitals, Greams Road, Chennai
Yamuna Devi Bakthavatchalam
Affiliation:
Microbiology, Christian Medical College, Vellore
Balaji Veeraraghavan
Affiliation:
Microbiology, Christian Medical College, Vellore
*
Corresponding author: Abdul Ghafur; Email: drghafur@hotmail.com

Abstract

In an Indian oncology setting, between August and December 2021, 56 patients, developed Burkholderia cenocepacia bacteremia. An investigation revealed a contaminated batch of the antiemetic drug palonosetron. The outbreak was terminated by withdrawing the culprit batch and the findings were reported promptly to regulatory authorities.

Type
Concise Communication
Copyright
© The Author(s), 2024. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America

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