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Patient, Provider, and Practice Characteristics Associated with Inappropriate Antimicrobial Prescribing in Ambulatory Practices

Published online by Cambridge University Press:  30 January 2018

Monica L. Schmidt*
Affiliation:
Center for Outcomes Research and Evaluation, Carolinas HealthCare System, Charlotte, North Carolina
Melanie D. Spencer
Affiliation:
Center for Outcomes Research and Evaluation, Carolinas HealthCare System, Charlotte, North Carolina
Lisa E. Davidson
Affiliation:
Division of Infectious Disease, Carolinas Medical Center, Carolinas HealthCare System, Charlotte, North Carolina
*Corresponding
Address correspondence to Melanie D. Spencer, PhD, MBA, Center for Outcomes Research and Evaluation, 1540 Garden Terrace Suite 406, Carolinas HealthCare System, Charlotte, North Carolina 28203 (melanie.spencer@carolinashealthcare.org).

Abstract

OBJECTIVE

To reduce inappropriate antimicrobial prescribing across ambulatory care, understanding the patient-, provider-, and practice-level characteristics associated with antibiotic prescribing is essential. In this study, we aimed to elucidate factors associated with inappropriate antimicrobial prescribing across urgent care, family medicine, and pediatric and internal medicine ambulatory practices.

DESIGN, SETTING, AND PARTICIPANTS

Data for this retrospective cohort study were collected from outpatient visits for common upper respiratory conditions that should not require antibiotics. The cohort included 448,990 visits between January 2014 and May 2016. Carolinas HealthCare System urgent care, family medicine, internal medicine and pediatric practices were included across 898 providers and 246 practices.

METHODS

Prescribing rates were reported per 1,000 visits. Indications were defined using the International Classification of Disease, Ninth and Tenth Revisions, Clinical Modification (ICD-9/10-CM) criteria. In multivariable models, the risk of receiving an antibiotic prescription was reported with adjustment for practice, provider, and patient characteristics.

RESULTS

The overall prescribing rate in the study cohort was 407 per 1,000 visits (95% confidence interval [CI], 405–408). After adjustment, adult patients seen by an advanced practice practitioner were 15% more likely to receive an antimicrobial than those seen by a physician provider (incident risk ratio [IRR], 1.15; 95% CI, 1.03–1.29). In the pediatric sample, older providers were 4 times more likely to prescribe an antimicrobial than providers aged ≤30 years (IRR, 4.21; 95% CI, 2.96–5.97).

CONCLUSIONS

Our results suggest that patient, practice, and provider characteristics are associated with inappropriate antimicrobial prescribing. Future research should target antibiotic stewardship programs to specific patient and provider populations to reduce inappropriate prescribing compared to a “one size fits all” approach.

Infect Control Hosp Epidemiol 2018;39:307–315

Type
Original Articles
Copyright
© 2018 by The Society for Healthcare Epidemiology of America. All rights reserved 

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