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Variability in antimicrobial use among infants born at <33 weeks gestational age

Published online by Cambridge University Press:  17 September 2021

Joseph Y. Ting*
Affiliation:
Department of Pediatrics, University of British Columbia, Vancouver, British Colombia, Canada
Ashley Roberts
Affiliation:
Department of Pediatrics, University of British Columbia, Vancouver, British Colombia, Canada
Ayman Abou Mehrem
Affiliation:
Department of Pediatrics, University of Calgary, Calgary, Alberta, Canada
Faiza Khurshid
Affiliation:
Department of Pediatrics, Queen’s University, Kingston, Ontario, Canada
Christine Drolet
Affiliation:
Centre Mère-Enfant Soleil, CHU de Québec, Laval University, Quebec City, Québec, Canada
Luis Monterrosa
Affiliation:
Department of Pediatrics, Saint John Regional Hospital, Saint John, New Brunswick, Canada
Eugene W. Yoon
Affiliation:
Maternal-infant Care Research Centre, Mount Sinai Hospital, Toronto, Ontario, Canada
Prakesh S. Shah
Affiliation:
Maternal-infant Care Research Centre, Mount Sinai Hospital, Toronto, Ontario, Canada Department of Pediatrics, Mount Sinai Hospital and University of Toronto, Ontario, Canada
*
Author for correspondence: Joseph Y. Ting, E-mail: yukjosep@ualberta.ca

Abstract

Excessive antimicrobial use is associated with adverse neonatal outcomes. In our cohort of 27,163 infants born at <33 weeks gestational age, the first week after birth accounted for the highest rates of antimicrobial use, and variability across sites persisted after adjustment for patient characteristics correlated with illness severity.

Type
Concise Communication
Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America

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Footnotes

a

A full list of CNN investigators and their affiliations is provided in the Acknowledgments.

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