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Are There Regional Variations in the Diagnosis, Surveillance, and Control of Methicillin-Resistant Staphylococcus aureus?

  • Hervé M. Richet (a1), Mohamed Benbachir (a2), Derek F. J. Brown (a3), Helen Giamarellou (a4), Ian Gould (a5), Marija Gubina (a6), Piotr Heczko (a7), Smilja Kalenic (a8), Marina Pana (a9), Didier Pittet (a10), Saida Ben Redjeb (a11), Jiri Schindler (a12), Carlos Starling (a13), Marc J. Struelens (a14), Wolfgang Witte (a15), William R. Jarvis (a1) and International Network for the Study and Prevention of Emerging Antimicrobial Resistance (INSPEAR)...

Abstract

Objective:

To assess the way healthcare facilities (HCFs) diagnose, survey, and control methicillin-resistant Staphylococcus aureus (MRSA).

Design:

Questionnaire.

Setting:

Ninety HCFs in 30 countries.

Results:

Evaluation of susceptibility testing methods showed that 8 laboratories (9%) used oxacillin disks with antimicrobial content different from the one recommended, 12 (13%) did not determine MRSA susceptibility to vancomycin, and 4 (4.5%) reported instances of isolation of vancomycin-resistant S. aureus but neither confirmed this resistance nor alerted public health authorities. A MRSA control program was reported by 55 (61.1%) of the HCFs. The following isolation precautions were routinely used: hospitalization in a private room (34.4%), wearing of gloves (62.2%), wearing of gowns (44.4%), hand washing by healthcare workers (53.3%), use of an isolation sign on the patient's door (43%), or all four. When the characteristics of HCFs with low incidence rates (< 0.4 per 1,000 patient-days) were compared with those of HCFs with high incidence rates (P = 0.4 per 1,000 patient-days), having a higher mean number of beds per infection control nurse was the only factor significantly associated with HCFs with high incidence rates (834 vs 318 beds; P = .02).

Conclusion:

Our results emphasize the urgent need to strengthen the microbiologic and epidemiologic capacities of HCFs worldwide to prevent MRSA transmission and to prepare them to address the possible emergence of vancomycin-resistant S. aureus.

Copyright

Corresponding author

Laboratoire de Bactériologie-Virologie-Hygiène Hospitalière, Institut de Biologie des Hôpitaux de Nantes, 9, quai Moncousu, BP 1005, 44093 Nantes cedex 01, France

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Infection Control & Hospital Epidemiology
  • ISSN: 0899-823X
  • EISSN: 1559-6834
  • URL: /core/journals/infection-control-and-hospital-epidemiology
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