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Association of an Active Surveillance and Decolonization Program on Incidence of Clinical Cultures Growing Staphylococcus aureus in the Neonatal Intensive Care Unit

  • Annie Voskertchian (a1), Ibukunoluwa C. Akinboyo (a1), Elizabeth Colantuoni (a2), Julia Johnson (a3) and Aaron M. Milstone (a1)...


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Corresponding author

Address correspondence to Aaron M. Milstone, MD, MHS, 200 N Wolfe St, Baltimore MD 21287 (


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PREVIOUS PRESENTATION. These data were presented in part at IDWeek 2017 on October 7, 2017, in San Diego, California, in the following poster (2170): Voskertchian A, Akinboyo I, Johnson J, Colantuoni E, Sick-Samuels A, Aucott SW, Milstone AM. Association of Active Surveillance and Decolonization Program on Incidence of Clinical Cultures Growing Staphylococcus aureus in the Neonatal Intensive Care Unit.



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1. Verstraete, E, Boelens, J, De Coen, K, et al. Healthcare-associated bloodstream infections in a neonatal intensive care unit over a 20-year period (1992–2011): trends in incidence, pathogens, and mortality. Infect Control Hosp Epidemiol 2014;35:511518.
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4. Popoola, VO, Colantuoni, E, Suwantarat, N, et al. Active surveillance cultures and decolonization to reduce Staphylococcus aureus infections in the neonatal intensive care unit. Infect Control Hosp Epidemiol 2016;37:381387.
5. Delaney, HM, Wang, E, Melish, M. Comprehensive strategy including prophylactic mupirocin to reduce Staphylococcus aureus colonization and infection in high-risk neonates. J Perinatol 2013;33:313318.
6. Wisgrill, L, Zizka, J, Unterasinger, L, et al. Active surveillance cultures and targeted decolonization are associated with reduced methicillin-susceptible Staphylococcus aureus infections in VLBW infants. Neonatology 2017;112:267273.
7. Whittington, MD, Atherly, AJ, Curtis, DJ, Lindrooth, RC, Bradley, CJ, Campbell, JD. Recommendations for methicillin-resistant Staphylococcus aureus prevention in adult ICUs: a cost-effectiveness analysis. Crit Care Med 2017;45:13041310.
8. Pierce, R, Bryant, K, Elward, A, Lessler, J, Milstone, AM. Bacterial infections in neonates following mupirocin-based MRSA decolonization: a multicenter cohort study. Infect Control Hosp Epidemiol 2017;38:930936.
9. Hayden, MK, Lolans, K, Haffenreffer, K, et al. Chlorhexidine and mupirocin susceptibility of methicillin-resistant Staphylococcus aureus isolates in the REDUCE-MRSA trial. J Clin Microbiol 2016;54:27352742.


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