Hostname: page-component-76fb5796d-skm99 Total loading time: 0 Render date: 2024-04-28T03:59:24.472Z Has data issue: false hasContentIssue false
  • English
  • Français

Breakthrough Varicella Infection in a Healthcare Worker Despite Immunity After Varicella Vaccination

Published online by Cambridge University Press:  02 January 2015

Rebecca Wurtz  and
Irene J. Check
Rebecca Wurtz*
Affiliation:
Departments of Medicine and Pathology, Evanston Hospital, Evanston, Illinois
Irene J. Check
Affiliation:
Northwestern Medical School, Chicago, Illinois
*
Evanston Hospital, 2650 Ridge Ave, Evanston, IL 60201
Get access Rights & Permissions [Opens in a new window]

Abstract

Although varicella vaccination is recommended for varicella-susceptible healthcare workers (HCWs), breakthrough infection after vaccination is not unusual, especially following household exposures. We report breakthrough varicella in a vaccinated HCW and review the data on breakthrough infection and concerns for the healthcare setting.

Type
Concise Communications
Information
Infection Control & Hospital Epidemiology , Volume 20 , Issue 8 , August 1999 , pp. 561 - 562
Copyright
Copyright © The Society for Healthcare Epidemiology of America 1999

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Centers for Disease Control and Prevention. Varicella prevention. Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR 1996;45(RR-11):1–37.Google Scholar
2.Gershon, AA, Steinberg, SP, the National Institute of Allergy and Infectious Diseases Varicella Vaccine Collaborative Study Group. Live attenuated varicella vaccine: protection in healthy adults compared with leukemic children. J Infect Dis 1990;161:661–666.Google Scholar
3.Arvin, AM, Gershon, AA. Live attenuated varicella vaccine. Annu Rev Microbiol 1996;50:59–100.Google Scholar
4.Nader, S, Bergen, R, Sharp, M, Arvin, AM. Age-related differences in cell-mediated immunity to varicella-zoster virus among children and adults immunized with live attenuated varicella vaccine. J Infect Dis 1995;171:13.Google Scholar
5.Gershon, AA, Steinberg, SP, LaRussa, P, Ferrara, A, Hammerschlag, M, Gelb, L. Immunization of healthy adults with live attenuated varicella vaccine. J Infect Dis 1988;158:132–137.CrossRefGoogle ScholarPubMed
6.White, CJ, Kuter, BJ, Ngai, A, Hildebrand, CS, Isganitis, KL, Patterson, CM, et al. Modified cases of chickenpox after varicella vaccination: correlation of protection with antibody response. Pediatr Infect Dis J 1992;11:19–23.CrossRefGoogle ScholarPubMed
7.Krah, DL. Assays for antibodies to varicella-zoster virus. Infect Dis Clin North Am 1996;10:507–528.Google Scholar
8.Check, IJ. Vaccines and immunity assessment: diagnostic immunology laboratory issues. Clinical Immunology Newsletter 1994;14:117–119.Google Scholar