Skip to main content

Comparison of Antibiotic Susceptibility Patterns of Bacterial Isolates Based on Time From Hospitalization and Culture Source: Implications for Hospital Antibiograms

  • Yaakov Dickstein (a1), Yuval Geffen (a2), Leonard Leibovici (a3) and Mical Paul (a1)

We assessed the effects of time from hospitalization and culture source on bacterial susceptibility profiles. Increasing resistance correlated with increasing time from hospitalization for all bacterial groups, with 7 days in hospital representing the best time point for dichotomizing susceptibility rates rather than 48 hours. Antibiograms based on isolates from any source best represented susceptibility profiles.

Infect. Control Hosp. Epidemiol. 2016;37(2):212–214

Corresponding author
Address correspondence to Dr. Yaakov Dickstein, Division of Infectious Diseases, Rambam Health Care Campus, HaAliya HaShniya St. 8, Haifa, Israel 3109601 (
Hide All

PREVIOUS PRESENTATION. The data from this article was presented as a poster at the 2015 Conference of the Israeli Society of Infectious Diseases.

Hide All
1. Hindler JF, Stelling J. Analysis and presentation of cumulative antibiograms: a new consensus guideline from the Clinical and Laboratory Standards Institute. Clin Infect Dis 2007;44:867873.
2. Bantar C, Alcazar G, Franco D, et al. Are laboratory-based antibiograms reliable to guide the selection of empirical antimicrobial treatments in patients with hospital-acquired infections? J Antimicrob Chemother 2007;59:140143.
3. Analysis and Presentation of Cumulative Antimicrobial Susceptibility Test Data. 3rd ed. (CLSI publication M39-A3). Wayne, PA: Clinical and Laboratory Standards Institute, 2009.
4. Magiorakos AP, Srinivasan A, Carey RB, et al. Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance. Clin Microbiol Infect 2012;18:268281.
5. Garner JS, Jarvis WR, Emori TG, Horan TC, Hughes JM. CDC definitions for nosocomial infections, 1988. Am J Infect Control 1988;16:128140.
6. Cardoso T, Almeida M, Friedman ND, et al. Classification of healthcare-associated infection: a systematic review 10 years after the first proposal. BMC Med 2014;12:40.
7. Kuster SP, Ruef C, Zbinden R, et al. Stratification of cumulative antibiograms in hospitals for hospital unit, specimen type, isolate sequence and duration of hospital stay. J Antimicrob Chemother 2008;62:14511461.
8. Leibovici L, Schønheyder H, Pitlik SD, Samra Z, Møller JK. Bacteraemia caused by hospital-type micro-organisms during hospital stay. J Hosp Infect 2000;44:3136.
9. Draper HM, Farland JB, Heidel RE, May LS, Suda KJ. Comparison of bacteria isolated from emergency department patients versus hospitalized patients. Am J Health Syst Pharm 2013;70:21242128.
10. Hombach M, Bloemberg GV, Böttger EC. Effects of clinical breakpoint changes in CLSI guidelines 2010/11 and EUCAST guidelines 2011 on antibiotic susceptibility test reporting of Gram-negative bacilli. J Antimicrob Chemother 2012;67:622632.
Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Infection Control & Hospital Epidemiology
  • ISSN: 0899-823X
  • EISSN: 1559-6834
  • URL: /core/journals/infection-control-and-hospital-epidemiology
Please enter your name
Please enter a valid email address
Who would you like to send this to? *


Altmetric attention score

Full text views

Total number of HTML views: 4
Total number of PDF views: 31 *
Loading metrics...

Abstract views

Total abstract views: 215 *
Loading metrics...

* Views captured on Cambridge Core between September 2016 - 17th January 2018. This data will be updated every 24 hours.