Skip to main content
×
Home
    • Aa
    • Aa

Comparison of the Burdens of Hospital-Onset, Healthcare Facility-Associated Clostridium difficile Infection and of Healthcare-Associated Infection due to Methicillin-Resistant Staphylococcus aureus in Community Hospitals

  • Becky A. Miller (a1), Luke F. Chen (a1), Daniel J. Sexton (a1) and Deverick J. Anderson (a1)
Abstract

We sought to determine the burden of nosocomial Clostridium difficile infection in comparison to other healthcare-associated infections (HAIs) in community hospitals participating in an infection control network. Our data suggest that C. difficilehas replaced MRSA as the most common etiology of HAI in community hospitals in the southeastern United States.

Copyright
Corresponding author
Box 102359, Duke University Medical Center, Durham, NC 27710 (becky.miller@duke.edu)
References
Hide All
1. DallalRM, HarbrechtBG, BoujoukasAJ, et al. Fulminant Clostridium difficile: an underappreciated and increasing cause of death and complications. Ann Surg 2002;235:363372.
2. McDonaldLC, OwingsM, JerniganDB. Clostridium difficile infection in patients discharged from US short-stay hospitals, 1996-2003. Emerg Infect Dis 2006;12:409415.
3. MusherDM, AslamS, LoganN, et al. Relatively poor outcome after treatment of Clostridium difficile colitis with metronidazole. Clin Infect Dis 2005;40:15861590.
4. PepinJ, ValiquetteL, AlaryME, et al. Clostridium difficile-associated diarrhea in a region of Quebec from 1991 to 2003: a changing pattern of disease severity. CMAJ 2004;171:466472.
5. DubberkeER, ButlerAM, YokoeDS, et al. Multicenter study of surveillance for hospital-onset Clostridium difficile infection by the use of ICD-9-CM diagnosis codes. Infect Control Hosp Epidemiol 2010;31:262268.
6. AndersonDJ, SextonDJ, KanafaniZA, AutenG, KayeKS. Severe surgical site infection in community hospitals: epidemiology, key procedures, and the changing prevalence of methicillin-resistant Staphylococcus aureus . Infect Control Hosp Epidemiol 2007;28:10471053.
7. HoranTC, AndrusM, DudeckMA. CDC/NHSN surveillance definition of health care-associated infection and criteria for specific types of infections in the acute care setting. Am J Infect Control 2008;36:309332.
8. McDonaldLC, CoignardB, DubberkeE, SongX, HoranT, KuttyPK. Recommendations for surveillance of Clostridium difficile-associated disease. Infect Control Hosp Epidemiol 2007;28:140145.
9. KayeKS, EngemannJJ, FulmerEM, ClarkCC, NogaEM, SextonDJ. Favorable impact of an infection control network on nosocomial infection rates in community hospitals. Infect Control Hosp Epidemiol 2006;27:228232.
10. KayeKS, SloaneR, SextonDJ, SchmaderKA. Risk factors for surgical site infections in older people. J Am Geriatr Soc 2006;54:391396.
11. McDonaldLC, KillgoreGE, ThompsonA, et al. An epidemic, toxin gene-variant strain of Clostridium difficile . N Engl J Med 2005;353:24332441.
12. LooVG, LibmanMD, MillerMA, et al. Clostridium difficile, a formidable foe. CMAJ 2004;171:4748.
13. LooVG, PoirierL, MillerMA, et al. A predominantly clonal multi-institutional outbreak of Clostridium difficile-associated diarrhea with high morbidity and mortality. N Engl J Med 2005;353:24422449.
14. BirgandG, MilianiK, CarbonneA, AstagneauP. Is high consumption of antibiotics associated with Clostridium difficile polymerase chain reaction-ribotype 027 infections in France? Infect Control Hosp Epidemiol 2010;31:302305.
15. O'ConnorJR, JohnsonS, GerdingDN. Clostridium difficile infection caused by the epidemic BI/NAP1/027 strain. Gastroenterology 2009;136:19131924.
16. KallenAJ, MuY, BulensS, et al. Health care-associated invasive MRSA infections, 2005-2008. JAMA 2010;304:641647.
17. AndersonDJ, SextonDJ. Whither infection control in community hospitals? musings about the near future. Infect Control Hosp Epidemiol 2008;29:10711073.
Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Infection Control & Hospital Epidemiology
  • ISSN: 0899-823X
  • EISSN: 1559-6834
  • URL: /core/journals/infection-control-and-hospital-epidemiology
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×

Metrics

Altmetric attention score

Full text views

Total number of HTML views: 0
Total number of PDF views: 44 *
Loading metrics...

Abstract views

Total abstract views: 654 *
Loading metrics...

* Views captured on Cambridge Core between September 2016 - 19th October 2017. This data will be updated every 24 hours.