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Current Definitions of Central Line–Associated Bloodstream Infection Is the Emperor Wearing Clothes?

  • Daniel J. Sexton (a1), Luke F. Chen (a1) and Deverick J. Anderson (a1)
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Box 102359, Duke University Medical Center, Durham, North Carolina, 27710, (
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1. P Pronovost , D Needham , S Berenholtz , et al.An intervention to decrease catheter-related BSIs in the ICU. N Engl J Med 2006;355(26):27252732.

6. J MacFie , C O'Boyle , CJ Mitchell , PM Buckley , D Johnstone , P Sudworth . Gut origin of sepsis: a prospective study investigating associations between bacterial translocation, gastric microflora, and septic morbidity. Gut 1999;45(2):223228.

13. MP Weinstein , ML Towns , SM Quartey , et al.The clinical significance of positive blood cultures in the 1990s: a prospective comprehensive evaluation of the microbiology, epidemiology, and outcome of bacteremia and fungemia in adults. Clin Infect Dis 1997;24(4):584602.

14. MP Weinstein , LB Relier , IR Murphy , KA Lichtenstein . The clinical significance of positive blood cultures: a comprehensive analysis of 500 episodes of bacteremia and fungemia in adults. I. Laboratory and epidemiologic observations. Rev Infect Dis 1983;5(1):3553.

16. KK Hall , JA Lyman . Updated review of blood culture contamination. Clin Microbiol Rev 2006;19(4):788802.

21. CM Sassetti , EJ Rubin . The open book of infectious diseases. Nat Med 2007;13(3):279280.

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Infection Control & Hospital Epidemiology
  • ISSN: 0899-823X
  • EISSN: 1559-6834
  • URL: /core/journals/infection-control-and-hospital-epidemiology
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