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Phantom Prescribing: Examining the Frequency of Antimicrobial Prescriptions Without a Patient Visit

  • Benjamin N. Riedle (a1), Linnea A. Polgreen (a2), Joseph E. Cavanaugh (a1), Mary C. Schroeder (a2) and Philip M. Polgreen (a3) (a4)...
Abstract
OBJECTIVE

To investigate the scale of antimicrobial prescribing without a corresponding visit, and to compare the attributes of patients who received antimicrobials with a corresponding visit with those who did not have a visit.

DESIGN

Retrospective cohort.

METHODS

We followed up 185,010 Medicare patients for 1 year after an acute myocardial infarction. For each antimicrobial prescribed, we determined whether the patient had an inpatient, outpatient, or provider claim in the 7 days prior to the antimicrobial prescription being filled. We compared the proportions of patient characteristics for those prescriptions associated with a visit and without a visit (ie, phantom prescriptions). We also compared the rates at which different antimicrobials were prescribed without a visit.

RESULTS

We found that of 356,545 antimicrobial prescriptions, 14.75% had no evidence of a visit in the week prior to the prescription being filled. A higher percentage of patients without a visit were identified as white (P<.001) and female (P<.001). Patients without a visit had a higher likelihood of survival and fewer additional cardiac events (acute myocardial infarction, cardiac arrest, stroke, all P<.001). Among the antimicrobials considered, amoxicillin, penicillin, and agents containing trimethoprim and methenamine were much more likely to be prescribed without a visit. In contrast, levofloxacin, metronidazole, moxifloxacin, vancomycin, and cefdinir were much less likely to be prescribed without a visit.

CONCLUSIONS

Among this cohort of patients with chronic conditions, phantom prescriptions of antimicrobials are relatively common and occurred more frequently among those patients who were relatively healthy.

Infect Control Hosp Epidemiol 2017;38:273–280

Copyright
Corresponding author
Address correspondence to Philip M. Polgreen, MD, MPH, University of Iowa, Departments of Internal Medicine and Epidemiology, UIHC SW34-Q GH, Iowa City, IA 52242 (philip-polgreen@uiowa.edu).
Footnotes
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Previous presentation: American Pharmacists’ Association Meeting; Baltimore, Maryland; March 5, 2016.

Footnotes
References
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Infection Control & Hospital Epidemiology
  • ISSN: 0899-823X
  • EISSN: 1559-6834
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