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Review of Clinical Trials of Skin Antiseptic Agents Used to Reduce Blood Culture Contamination

  • Anurag Malani (a1) (a2) (a3), Kim Trimble (a2), Vikas Parekh (a2), Carol Chenoweth (a1) (a2), Samuel Kaufman (a4) (a2) and Sanjay Saint (a5) (a4) (a2) (a3)...

False-positive blood culture results may lead to prolonged hospitalization, inappropriate antibiotic administration, and increased healthcare costs. We conducted a review of the literature to assess the effect of skin antiseptic agents on the rate of false-positive blood culture Results. We found no clear evidence to suggest which antiseptic should be used to prevent false-positive Results. Studies suggest, however, a possible benefit from the use of prepackaged skin antiseptic kits and alcohol-containing antiseptics.

Corresponding author
Veterans Affairs Ann Arbor Healthcare System, 2215 Fuller Rd., Ann Arbor, MI 48105 (
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Infection Control & Hospital Epidemiology
  • ISSN: 0899-823X
  • EISSN: 1559-6834
  • URL: /core/journals/infection-control-and-hospital-epidemiology
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