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Review of Clinical Trials of Skin Antiseptic Agents Used to Reduce Blood Culture Contamination

Published online by Cambridge University Press:  02 January 2015

Anurag Malani ,
Kim Trimble ,
Vikas Parekh ,
Carol Chenoweth ,
Samuel Kaufman  and
Sanjay Saint
Anurag Malani*
Affiliation:
Division of Infectious Diseases, University of Michigan Medical School, Ann Arbor, Michigan Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan Veterans Affairs Ann Arbor Healthcare System, Ann Arbor, Michigan
Kim Trimble
Affiliation:
Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan
Vikas Parekh
Affiliation:
Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan
Carol Chenoweth
Affiliation:
Division of Infectious Diseases, University of Michigan Medical School, Ann Arbor, Michigan Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan
Samuel Kaufman
Affiliation:
Patient Safety Enhancement Program, University of Michigan Medical School, Ann Arbor, Michigan Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan
Sanjay Saint
Affiliation:
Health Services Research and Development Service, University of Michigan Medical School, Ann Arbor, Michigan Patient Safety Enhancement Program, University of Michigan Medical School, Ann Arbor, Michigan Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan Veterans Affairs Ann Arbor Healthcare System, Ann Arbor, Michigan
*
Veterans Affairs Ann Arbor Healthcare System, 2215 Fuller Rd., Ann Arbor, MI 48105 (malanian@med.umich.edu)
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Abstract

False-positive blood culture results may lead to prolonged hospitalization, inappropriate antibiotic administration, and increased healthcare costs. We conducted a review of the literature to assess the effect of skin antiseptic agents on the rate of false-positive blood culture Results. We found no clear evidence to suggest which antiseptic should be used to prevent false-positive Results. Studies suggest, however, a possible benefit from the use of prepackaged skin antiseptic kits and alcohol-containing antiseptics.

Type
Concise Communications
Information
Infection Control & Hospital Epidemiology , Volume 28 , Issue 7 , July 2007 , pp. 892 - 895
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2007

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