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Effectiveness of Disinfectants Against Candida auris and Other Candida Species

  • Jennifer L. Cadnum (a1), Aaron A. Shaikh (a2), Christina T. Piedrahita (a1), Thriveen Sankar (a1), Annette L. Jencson (a1), Emily L. Larkin (a3) (a4), Mahmoud A. Ghannoum (a3) (a4) and Curtis J. Donskey (a2) (a5)...

Contaminated surfaces are a suspected source for dissemination of the globally emerging pathogen Candida auris. In laboratory testing, sporicidal and improved hydrogen peroxide disinfectants were highly effective against C. auris, C. glabrata, and C. albicans. The widely used quaternary ammonium disinfectants exhibited relatively poor activity against all of the Candida species.

Infect Control Hosp Epidemiol 2017;38:1240–1243

Corresponding author
Address correspondence to Curtis J. Donskey, MD, Geriatric Research, Education, and Clinical Center 1110W, Cleveland VA Medical Center, 10701 East Boulevard, Cleveland, Ohio 44106 (
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1. Vallabhaneni, S, Kallen, A, Tsay, S, et al. Investigation of the first seven reported cases of Candida auris, a globally emerging invasive, multidrug-resistant fungus—United States, May 2013–August 2016. Am J Transplant 2017;17:296299.
2. Schelenz, S, Hagen, F, Rhodes, JL, et al. First hospital outbreak of the globally emerging Candida auris in a European hospital. Antimicrob Resist Infect Control 2016;5:35.
3. Larkin, E, Hager, C, Chandra, J, et al. The emerging Candida auris: characterization of growth phenotype, virulence factors, antifungal activity, and effect of SCY-078, a novel glucan synthesis inhibitor, on growth morphology and biofilm formation. Antimicrob Agents Chemother 2017;Feb 21. pii: AAC 02396–16.
4. Fungal diseases: Candida auris. Centers for Disease Control and Preventions website. Updated 2017. Accessed July 10, 2017.
5. List K: EPA’s registered antimicrobial products effective against Clostridium difficile spores. US Environmental Protection Agency website. Published 2017. Accessed July 10, 2017.
6. EPA MLB SOP MB-35-00: OECD Quantitative method for evaluating the efficacy of liquid antimicrobials against Candida auris on hard, non-porous surfaces. US Environmental Protection Agency Office of Pesticide Programs website. Published 2017. Accessed July 10, 2017.
7. ASTM International, Designation E2197: standard quantitative disk carrier test method for determining bactericidal, virucidal, fungicidal, mycobactericidal, and sporicidal activities of chemicals, 2011.
8. AOAC Official Method 961.02 Germicidal spray products as disinfectants. Microchem Laboratory website. Published 2015. Accessed July 10, 2017.
9. Environmental Protection Agency. Product performance test guidelines OCSPP 810.2200: disinfectants for use on hard surfaces—efficacy data recommendations. US Federal Regulations website. Published 2012. Accessed July 10, 2017.
10. Piedrahita, CT, Cadnum, JL, Jencson, AL, Shaikh, AA, Ghannoum, MA, Donskey, CJ. Environmental surfaces in healthcare facilities are a potential source for transmission of Candida auris and other Candida species. Infect Control Hosp Epidemiol 2017;13. doi: 10.1017/ice.2017.127 [Epub July 11, 2017].
11. Pfaller, MA. Nosocomial candidiasis: emerging species, reservoirs, and modes of transmission. Clin Infect Dis 1996;22(Suppl 2):S89S94.
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Infection Control & Hospital Epidemiology
  • ISSN: 0899-823X
  • EISSN: 1559-6834
  • URL: /core/journals/infection-control-and-hospital-epidemiology
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