Skip to main content
×
Home
    • Aa
    • Aa

Hospital-Onset Clostridium difficile Infection Rates in Persons with Cancer or Hematopoietic Stem Cell Transplant: A C3IC Network Report

  • Mini Kamboj (a1), Crystal Son (a1), Sherry Cantu (a2), Roy F. Chemaly (a2), Jeanne Dickman (a3), Erik Dubberke (a4) (a5), Lisa Engles (a6), Theresa Lafferty (a7), Gale Liddell (a8), Mary Ellen Lesperance (a6), Julie E. Mangino (a3), Stacy Martin (a9), Jennie Mayfield (a4), Sapna A. Mehta (a10), Susan O'Rourke (a11), Cheryl S. Perego (a2), Randy Taplitz (a12), Janet Eagan (a1) and Kent A. Sepkowitz (a1)...
Abstract

A multicenter survey of 11 cancer centers was performed to determine the rate of hospital-onset Clostridium difficile infection (HO-CDI) and surveillance practices. Pooled rates of HO-CDI in patients with cancer were twice the rates reported for all US patients (15.8 vs 7.4 per 10,000 patient-days). Rates were elevated regardless of diagnostic test used.

Copyright
Corresponding author
1275 York Avenue, New York, NY 10065 (kambojm@mskcc.org)
Linked references
Hide All

This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

2. A Anand , AE Glatt . Clostridium difficile infection associated with antineoplastic chemotherapy: a review. Clin Infect Dis 1993;17(1):109113.

3. M Gorschluter , A Glasmacher , C Hahn , et al.Clostridium difficile infection in patients with neutropenia. Clin Infect Dis 2001;33(6):786791.

4. VG Loo , L Poirier , MA Miller , et al.A predominantly clonal multi-institutional outbreak of Clostridium difficile-associated diarrhea with high morbidity and mortality. N Engl J Med 2005;353(23):24422449.

5. D Bobak , LM Arfons , RJ Creger , HM Lazarus . Clostridium difficile-associated disease in human stem cell transplant recipients: coming epidemic or false alarm? Bone Marrow Transplantation 2008;42(11):705713.

11. A Deshpande , V Pasupuleti , DD Rolston , et al.Diagnostic accuracy of real-time polymerase chain reaction in detection of Clostridium difficile in the stool samples of patients with suspected Clostridium difficile infection: a meta-analysis. Clin Infect Dis 2011;53(7):e81e90.

13. A Kaltsas , M Simon , LH Unruh , et al.Clinical and laboratory characteristics of Clostridium difficile infection in patients with discordant diagnostic test results. J Clinical Microbiol 2012:50(4):13031307.

Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Infection Control & Hospital Epidemiology
  • ISSN: 0899-823X
  • EISSN: 1559-6834
  • URL: /core/journals/infection-control-and-hospital-epidemiology
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 12 *
Loading metrics...

Abstract views

Total abstract views: 158 *
Loading metrics...

* Views captured on Cambridge Core between September 2016 - 21st July 2017. This data will be updated every 24 hours.