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How frequently are hospitalized patients colonized with carbapenem-resistant Enterobacteriaceae (CRE) already on contact precautions for other indications?

  • Katherine E. Goodman (a1), Patricia J. Simner (a2), Eili Y. Klein (a1) (a3) (a4), Abida Q. Kazmi (a2), Avinash Gadala (a5), Clare Rock (a5) (a6), Pranita D. Tamma (a7), Sara E. Cosgrove (a5) (a6), Lisa L. Maragakis (a5) (a6), Aaron M. Milstone (a1) (a5) (a7), for the CDC Prevention Epicenters Program (a1) (a2) (a3) (a4) (a5) (a6) (a7) and the CDC MIND-Healthcare Program (a1) (a2) (a3) (a4) (a5) (a6) (a7)...
Abstract

Using samples collected for VRE surveillance, we evaluated unit admission prevalence of carbapenem-resistant Enterobacteriaceae (CRE) perirectal colonization and whether CRE carriers (unknown to staff) were on contact precautions for other indications. CRE colonization at unit admission was infrequent (3.9%). Most CRE carriers were not on contact precautions, representing a reservoir for healthcare-associated CRE transmission.

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Corresponding author
Authors for correspondence: Katherine E. Goodman JD, 615 N. Wolfe Street, Baltimore, MD 21205. E-mail: Kgoodma7@jhu.edu. Aaron Milstone MD, MHS, 200 N Wolfe Street, Rubenstein 3141, Baltimore, MD 21287. E-mail: AMilsto1@jhmi.edu
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Cite this article: Goodman KE, et al. (2018). How frequently are hospitalized patients colonized with carbapenem-resistant Enterobacteriaceae (CRE) already on contact precautions for other indications? Infection Control & Hospital Epidemiology 2018, 39, 1491–1493. doi: 10.1017/ice.2018.236

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References
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1. Antibiotic resistance threats in the United States, 2013. Centers for Disease Control and Prevention website. https://www.cdc.gov/drugresistance/threat-report-2013/index.html. Published 2013. Accessed September 5, 2018.
2. Facility Guidance for Control of Carbapenem-resistant Enterobacteriaceae (CRE)— November 2015 Update CRE Toolkit. Centers for Disease Control and Prevention website. https://www.cdc.gov/hai/organisms/cre/cre-toolkit/index.html. Published 2015. Accessed September 5, 2018.
3. Simner, PJ, Martin, I, Opene, B, Tamma, PD, Carroll, KC, Milstone, AM. Evaluation of multiple methods for the detection of gastrointestinal colonization of carbapenem-resistant organisms from rectal swabs. J Clin Microbiol 2016;54:16641667.
4. Clinical and Laboratory Standards Institute. Performance Standards for Antimicrobial Susceptibility Testing, 28th ed., Supplement M100S. Wayne, PA: CLSI; 2018.
5. Pierce, VM, Simner, PJ, Lonsway, DR, et al. Modified carbapenem inactivation method for phenotypic detection of carbapenemase production among Enterobacteriaceae. J Clin Microbiol 2017; 55:23212333.
6. Woodworth, KR, Walters, MS, Weiner, LM, et al. Vital signs: containment of novel multidrug-resistant organisms and resistance mechanisms—United States, 20062017. Morb Mortal Wkly Rep 2018; 67: 396401.
7. Logan, LK, Weinstein, RA. The epidemiology of carbapenem-resistant Enterobacteriaceae: the impact and evolution of a global menace. J Infect Dis 2017;215 Suppl 1:S28S36.
8. McKinnell, JA, Miller, LG, Eells, SJ, Cui, E, Huang, SS. A systematic literature review and meta-analysis of factors associated with methicillin-resistant Staphylococcus aureus colonization at time of hospital or intensive care unit admission. Infect Control Hosp Epidemiol 2013; 34:10771086.
9. Simner, PJ, Goodman, KE, Carroll, KC, Harris, AD, Han, JH, Tamma, PD. Using patient risk factors to identify whether carbapenem-resistant Enterobacteriaceae infections are caused by carbapenemase-producing organisms. Open Forum Infect Dis 2018; 5: ofy094ofy094.
10. Goodman, KE, Simner, PJ, Tamma, PD, Milstone, AM. Infection control implications of heterogeneous resistance mechanisms in carbapenem-resistant Enterobacteriaceae (CRE). Expert Rev Anti-infect Ther 2016;14:95108.
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Infection Control & Hospital Epidemiology
  • ISSN: 0899-823X
  • EISSN: 1559-6834
  • URL: /core/journals/infection-control-and-hospital-epidemiology
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