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Lack of Benefit With Combination Therapy for Clostridium difficile Infection

  • Jessica C. Njoku (a1) (a2), Trevor C. Van Schooneveld (a1) (a3), Mark E. Rupp (a1) (a3), Keith M. Olsen (a1) (a2), Fang Qiu (a4), Jane L. Meza (a4) and Elizabeth D. Hermsen (a2) (a5)...

Limited data exist regarding combination therapy for Clostridium difficile infection (CDI). After adjusting for confounders in a cohort of patients with CDI and≥1 year old, combination therapy was not associated with significant differences in clinical outcomes, but it was associated with prolonged duration of therapy (1.22 days; 95% confidence interval, 1.03–1.44 days; P=.02).

Infect Control Hosp Epidemiol 2017;38:602–605

Corresponding author
Address correspondence to Jessica C. Njoku, PharmD, Good Shepherd Medical Center, 700 E Marshall Ave, Longview, TX 75601 (
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Infection Control & Hospital Epidemiology
  • ISSN: 0899-823X
  • EISSN: 1559-6834
  • URL: /core/journals/infection-control-and-hospital-epidemiology
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