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Overtreatment of Asymptomatic Bacteriuria: Identifying Targets for Improvement

  • Sarah Hartley (a1), Staci Valley (a1), Latoya Kuhn (a2), Laraine L. Washer (a1) (a3), Tejal Gandhi (a1), Jennifer Meddings (a1), Carol Chenoweth (a1), Anurag N. Malani (a4), Sanjay Saint (a1) (a2), Arjun Srinivasan (a5) and Scott A. Flanders (a1)...

Treatment of asymptomatic bacteriuria contributes to antimicrobial overuse in hospitalized patients. Indications for urine culture, treatment, and targets for improvement were evaluated in 153 patients. Drivers of antimicrobial overuse included fever with an alternative source, altered mental status, and leukocytosis, which led 435 excess days of antimicrobial therapy.

Infect Control Hosp Epidemiol 2014;00(0): 1–4

Corresponding author
Address correspondence to Sarah E. Hartley, MD, Clinical Assistant Professor, University of Michigan Health System, 1500 E Medical Center Drive, SPC 5736, Ann Arbor, Michigan 48109 (
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4. LE Nicolle , S Bradley , R Colgan , et al. Infectious Diseases Society of America guidelines for the diagnosis and treatment of asymptomatic bacteriuria in adults. Clin Infect Dis 2005;40:643654.

6. TM Hooton , SF Bradley , DD Cardenas , et al.Diagnosis, prevention, and treatment of catheter-associated urinary tract infection in adults: 2009 International Clinical Practice Guidelines from the Infectious Diseases Society of America. Clin Infect Dis 2010;50:625663.

10. SK Inouye . The dilemma of delirium: clinical and research controversies regarding diagnosis and evaluation of delirium in hospitalized elderly medical patients. Am J Med 1994;97:278288.

11. JA Leis , GW Rebick , N Daneman , et al. Reducing antimicrobial therapy for asymptomatic bacteriuria among noncatheterized inpatients: a proof-of-concept study. Clin Infect Dis 2014;58:980983.

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Infection Control & Hospital Epidemiology
  • ISSN: 0899-823X
  • EISSN: 1559-6834
  • URL: /core/journals/infection-control-and-hospital-epidemiology
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