Skip to main content
×
Home
    • Aa
    • Aa

Pseudo-Outbreak of Multidrug-Resistant Mycobacterium tuberculosis Associated With Presumed Laboratory Processing Contamination

  • Gonzalo Bearman (a1), Carlos Vaamonde (a1), Davise Larone (a2), Lewis Drusin (a1) and Gianna Zuccotti (a3)...
Abstract
Abstract

An investigation prompted by six positive cultures for multidrug-resistant Mycobacterium tuberculosis during a 7-week period found that an unusual resistance pattern, temporal proximity of laboratory processing, and identical DNA fingerprints supported the theory of cross-contamination. Laboratory processing procedures included specimen batching and multi-use vials of buffer solution. Processing procedures were changed and no additional cases of suspected cross-contamination have been observed. '(Infect Control Hosp Epidemiol 2002;23:622).

Copyright
Corresponding author
Division of Infectious Disease, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, Box 420, New York, NY 10021
Linked references
Hide All

This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

1. A Nitta , PT Davidson , ML de Koning , J Kilman . Misdiagnosis of multidrug resistant tuberculosis possibly due to laboratory errors. JAMA 1996;276:19801983.

3. VR Aber , BW Allen , DA Mitchison , P Ayuma , EA Edwards , AB Keyes . Quality control in tuberculosis bacteriology: I. Laboratory studies on isolated positive cultures and the efficacy of direct smear examination. Tubercle 1980;61:123133.

4. S Segal-Maurer , BN Kreisworth , JM Burns , et alMycobacterium tuberculosis specimen contamination revisited: the role of laboratory environmental control in a pseudo-outbreak. Infect Control Hosp Epidemiol 1998; 19:101105.

5. WJ Burman , RR Reves . Review of false-positive cultures for Mycobacterium tuberculosis and recommendations for avoiding unnecessary treatment. Clin Infect Dis 2000;31:13901395.

6. W Cronin , E Rodriguez , S Valway , et alPseudo-outbreak of tuberculosis in an acute care hospital: epidemiology and clinical implications. Infect Control Hosp Epidemiol 1998;19:345347.

7. JR Maurer , EP Desmond , MD Lesser , WD Jones Jr. False positive cultures of Mycobacterium-tuberculosis. Chest 1984;86:439443.

Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Infection Control & Hospital Epidemiology
  • ISSN: 0899-823X
  • EISSN: 1559-6834
  • URL: /core/journals/infection-control-and-hospital-epidemiology
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 2 *
Loading metrics...

Abstract views

Total abstract views: 21 *
Loading metrics...

* Views captured on Cambridge Core between September 2016 - 24th June 2017. This data will be updated every 24 hours.