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Sustained decrease in urine culture utilization after implementing a reflex urine culture intervention: A multicenter quasi-experimental study

Published online by Cambridge University Press:  30 January 2020

Jessica R. Howard-Anderson*
Affiliation:
Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia
Shanza Ashraf
Affiliation:
Office of Quality, Emory Healthcare, Atlanta, Georgia
Elizabeth C. Overton
Affiliation:
Office of Quality, Emory Healthcare, Atlanta, Georgia
Lisa Reif
Affiliation:
Emory University Hospital, Atlanta, Georgia
David J. Murphy
Affiliation:
Office of Quality, Emory Healthcare, Atlanta, Georgia Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia
Jesse T. Jacob
Affiliation:
Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia
*
Author for correspondence: Jessica Howard-Anderson, E-mail: Jrhowa4@emory.edu

Extract

Accurately diagnosing urinary tract infections (UTIs) in hospitalized patients remains challenging, requiring correlation of frequently nonspecific symptoms and laboratory findings. Urine cultures (UCs) are often ordered indiscriminately, especially in patients with urinary catheters, despite the Infectious Diseases Society of America guidelines recommending against routine screening for asymptomatic bacteriuria (ASB).1,2 Positive UCs can be difficult for providers to ignore, leading to unnecessary antibiotic treatment of ASB.2,3 Using diagnostic stewardship to limit UCs to situations with a positive urinalysis (UA) can reduce inappropriate UCs since the absence of pyuria suggests the absence of infection.4–6 We assessed the impact of the implementation of a UA with reflex to UC algorithm (“reflex intervention”) on UC ordering practices, diagnostic efficiency, and UTIs using a quasi-experimental design.

Type
Research Brief
Copyright
© 2020 by The Society for Healthcare Epidemiology of America. All rights reserved.

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Footnotes

PREVIOUS PRESENTATION: A preliminary version of this work was presented at the Society to Improve Diagnosis in Medicine Annual International Conference on November 5, 2018, in New Orleans, Louisiana.

References

Nicolle, LE, Gupta, K, Bradley, SF, et al.Clinical practice guideline for the management of asymptomatic bacteriuria: 2019 update by the Infectious Diseases Society of America. Clin Infect Dis 2019;68:e83e110.CrossRefGoogle ScholarPubMed
Leis, JA, Gold, WL, Daneman, N, Shojania, K, McGeer, A.Downstream impact of urine cultures ordered without indication at two acute-care teaching hospitals. Infect Control Hosp Epidemiol 2013;34:11131114.CrossRefGoogle ScholarPubMed
Spivak, ES, Burk, M, Zhang, R, et al.Management of bacteriuria in Veterans’ Affairs hospitals. Clin Infect Dis 2017;65:910917.CrossRefGoogle Scholar
Kayalp, D, Dogan, K, Ceylan, G, Senes, M, Yucel, D.Can routine automated urinalysis reduce culture requests? Clin Biochem 2013;46:12851289.CrossRefGoogle ScholarPubMed
Stovall, RT, Haenal, JB, Jenkins, TC, et al.A negative urinalysis rules out catheter-associated urinary tract infection in trauma patients in the intensive care unit. J Am Coll Surg 2013;217:162166.CrossRefGoogle ScholarPubMed
Simerville, JA, Maxted, WC, Pahira, JJ.Urinalysis: a comprehensive review. AFP 2005;71:11531162.Google ScholarPubMed
Munigala, S, Rojek, R, Wood, H, et al.Effect of changing urine testing orderables and clinician order sets on inpatient urine culture testing: Analysis from a large academic medical center. Infect Control Hosp Epidemiol 2019;40:281286.Google ScholarPubMed
Munigala, S, Jackups, RR, Poirier, RF, et al.Impact of order set design on urine culturing practices at an academic medical centre emergency department. BMJ Qual Saf 2018;27:587592.CrossRefGoogle ScholarPubMed
Epstein, L, Edwards, JR, Halpin, AL, et al.Evaluation of a novel intervention to reduce unnecessary urine cultures in intensive care units at a tertiary care hospital in Maryland, 2011–2014. Infect Control Hosp Epidemiol 2016;37:606609.CrossRefGoogle Scholar
Zalmanovici Trestioreanu, A, Lador, A, Sauerbrun-Cutler, M-T, Leibovici, L.Antibiotics for asymptomatic bacteriuria. Cochrane Database Syst Rev 2015;4:CD009534.Google ScholarPubMed
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