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Transient Detection of Plasma HIV-1 RNA During Postexposure Prophylaxis

  • Vincenzo Puro (a1), Giuseppe Calcagno (a2), Marco Anselmo (a2), Gisella Benvenuto (a2), Daria Trabattoni (a3), Mario Clerici (a3) and Giuseppe Ippolito (a1)...
Abstract

Transient plasma human immunodeficiency virus (HIV) copies were detected by nucleic-acid sequence-based amplification during combination antiretroviral prophylaxis in a healthcare worker who reported a percutaneous injury from a stylet and who remained HIV-antibody-negative. An HIV-specific T-helper response, assessed by interleukin-2 production, was observed when tested at 13 months following the exposure.

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IRCCS “Lazzaro Spallanzani, ” Centro di Riferimento AIDS, Servizio di Epidemiologia delle Malattie Infettive, Via Portuense, 292-00149 Rome, Italy
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Infection Control & Hospital Epidemiology
  • ISSN: 0899-823X
  • EISSN: 1559-6834
  • URL: /core/journals/infection-control-and-hospital-epidemiology
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