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Two Consecutive Outbreaks of Stenotrophomonas Maltophilia (Xanthomonas Maltophilia) in an Intensive-care Unit Defined by Restriction Fragment-Length Polymorphism Typing

  • Nancy Alfieri (a1), Karam Ramotar (a2), Pamela Armstrong (a1), Mary E. Spornitz (a1), Glenda Ross (a1), James Winnick (a1) and D. Roy Cook (a1)...
Abstract
AbstractObjective:

To investigate and control consecutive outbreaks of Stenotrophomonas maltophilia infections in intensive-care–unit (ICU) patients.

Design:

Epidemiological investigation; restriction fragment-length polymorphism typing by pulsed-field gel electrophoresis (PFGE) of genomic DNA of outbreak strains; institution of infection control measures to limit spread.

Setting:

The medical-surgical ICU in an 800-bed tertiary-care center in Calgary, Alberta, Canada.

Results:

S maltophilia was recovered from 14 ICU patients (12 infected, 2 colonized) between February 1993 and February 1994. Ten of the 14 patient isolates and 1 environmental isolate were available for PFGE typing. Patient isolates from 6 of the first 10 patients were identical. Isolates from the next 3 of 4 patients and an isolate recovered from a ventilator being used by a patient not infected with S maltophilia also were identical, but different from the first 6. The ventilator isolate was temporally associated with the latter 4 patients.

Conclusion:

Molecular typing allowed us to determine that there were two separate consecutive S maltophilia outbreaks rather than a single protracted outbreak. Recovery of S maltophilia from patient ventilators and an in-line suction catheter suggests that the organism may have been spread by cross-contamination from contaminated equipment or from an environmental source.

Copyright
Corresponding author
Infection Control, Calgary District Hospital Group, 7007–14 St SW, Calgary, Alberta T2V 1P9, Canada
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This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

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Infection Control & Hospital Epidemiology
  • ISSN: 0899-823X
  • EISSN: 1559-6834
  • URL: /core/journals/infection-control-and-hospital-epidemiology
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