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Use of Hypochlorite Solution to Decrease Rates of Clostridium difficile-Associated Diarrhea

Published online by Cambridge University Press:  02 January 2015

Kathleen M. McMullen ,
Jeanne Zack ,
Craig M. Coopersmith ,
Marin Kollef ,
Erik Dubberke  and
David K. Warren
Kathleen M. McMullen*
Affiliation:
Barnes-Jewish Hospital, St. Louis, Missouri
Jeanne Zack
Affiliation:
Missouri Baptist Hospital, St. Louis, Missouri
Craig M. Coopersmith
Affiliation:
Washington University, St. Louis, Missouri
Marin Kollef
Affiliation:
Washington University, St. Louis, Missouri
Erik Dubberke
Affiliation:
Washington University, St. Louis, Missouri
David K. Warren
Affiliation:
Washington University, St. Louis, Missouri
*
Mailstop 90-75-500, 4905 Forest Park Avenue, St. Louis, MO 63108 (kmm2742@bjc.org)
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Abstract

An increased rate of Clostridium difficile-associated diarrhea (CDAD) was noted in 2 intensive care units of a university-affiliated tertiary care facility. One unit instituted enhanced environmental cleaning with a hypochlorite solution in all rooms, whereas the other unit used hypochlorite solution only in rooms of patients with CDAD. The CDAD rates decreased in both units.

Information

Type
Concise Communication
Information
Infection Control & Hospital Epidemiology , Volume 28 , Issue 2 , February 2007 , pp. 205 - 207
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2007

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References

1.Barbut, F, Corthier, G, Charpak, Y, et al. Prevalence and pathogenicity of Clostridium difficile in hospitalized patients: a French multicenter study. Arch Intern Med 1996;156:1449–1454.Google Scholar
2.Gerding, DN, Johnson, S, Peterson, LR, Mulligan, ME, Silva, J Jr. Clostridium difficile-associated diarrhea and colitis. Infect Control Hosp Epidemiol 1995;16:459–477.Google Scholar
3.Johnson, S, Gerding, DN. Clostridium difficile-associated diarrhea. Clin Infect Dis 1998;26:1027–1034.CrossRefGoogle ScholarPubMed
4.Kyne, L, Sougioultzis, S, McFarland, VL, Kelly, CP. Underlying disease severity as a major risk factor for nosocomial Clostridium difficile diarrhea. Infect Control Hosp Epidemiol 2002;23:653–659.Google Scholar
5.Dial, S, Delaney, JAC, Barkun, AN, Suissa, S. Use of gastric acid-suppressive agents and the risk of community-acquired Clostridium difficile-associated disease. JAMA 2005;294:2989–2995.Google Scholar
6.Loo, VG, Poirier, L, Miller, M, et al. A predominantly clonal multi-institutional outbreak of Clostridium difficile-associated diarrhea with high morbidity and mortality. N Engl J Med 2005;353:2442–2449.Google Scholar
7.Warny, M, Pepin, J, Fang, A, et al. Toxin production by an emerging strain of Clostridium difficile associated with outbreaks of severe disease in North America and Europe. Lancet 2005;366:1079–1084.Google Scholar
8.Bartlett, JG, Perl, TM. The new Clostridium difficile—what does it mean? N Engl J Med 2005;353:2503–2505.Google Scholar
9.Kaatz, GW, Gitlin, SD, Schaberg, DR, et al. Acquisition of Clostridium difficile from the hospital environment. Am J Epidemiol 1998;127:1289–1294.CrossRefGoogle Scholar
10.Mayfield, JL, Leet, T, Miller, J, Mundy, LM. Environmental control to reduce transmission of Clostridium difficile. Clin Infect Dis 2000;31:995–1000.Google Scholar
11.Wilcox, MH, Fawley, WN, Wigglesworth, N, et al. Comparison of the effect of detergent versus hypochlorite cleaning on environmental contamination and incidence of Clostridium difficile infection. J Hosp Infect 2003;54:109–114.CrossRefGoogle ScholarPubMed