An abbreviated method for the surveillance of nosocomial urinary tract infection is described. Combining desirable features of both active and passive surveillance, this new method involves concurrent review of microbiology reports. Compared to traditional active surveillance methods which require review of individual patient charts, the abbreviated method requires only one-fifth the time commitment while maintaining a 98% sensitivity. Although some degree of overestimation is inherent in this method, the primary goals of surveillance—monitoring infection rates and identifying clusters of infection—should be preserved.

Handwashing practices are often based on tradition and belief. To develop sound rationale for handwashing practices, the physiologic and bacteriologic effects of handwashing must be examined. The purposes of this article are to review the three major microenvironments of the skin with their bacterial flora, to discuss physiologic and bacteriologic characteristics of the skin with particular reference to handwashing, and to describe current handwashing recommendations and practices.

To estimate the risk of hepatitis B virus (HBV) infection among hospital workers, we measured the prevalence of HBV infection in employees in five hospitals in different parts of the country and examined the effect of occupational and non-occupational factors on HBV prevalence. Among 5,697 persons studied, serologic markers of HBV infection were found in 807 (14%). Prevalence of infection was strongly related to race (Asian > Black > White), sex (male > female) and increasing age.

Risk related to health occupation, studied by examining the change in HBV prevalence with duration in occupational group, was most strongly correlated with frequency of contact with blood during work. Workers having frequent blood contact had the highest estimated infection rate (1.05 per 100 person-years) and those with moderate contact an intermediate infection rate, compared to a negligible infection rate in workers with no blood contact. Frequency of needle accidents had an independent, positive effect on HBV infection rates, while degree of patient contact had no effect. Infection risk was uniform among all hospitals for groups with frequent blood contact. Among different occupation groups, risk of HBV infection also correlated closely with degree of blood-needle contact during daily work. This study provides a general approach to assessing risk of HBV infection in hospital personnel, and indicates that risk may be most easily estimated by quantitating degree of blood-needle contact during daily work.

In July 1982, five Hartford hospitals embarked on a joint hospital-sponsored program to immunize high-risk employees against hepatitis B virus (HBV). The program included a questionnaire to characterize relative risk, serology for anti-HBs, vaccination and a follow-up survey of vaccine non-recipients.

Of 2,065 employees who were considered to be at high-risk for infection with HBV, 1,894 (91.7%) responded to the screening questionnaire and 1,279 (67.5%) were tested for anti-HBs serology. The prevalence of antibody varied from hospital to hospital; the highest prevalence (10.9%) was observed at one of the urban university-affiliated community hospitals and the lowest prevalence (4.1%) was reported from the smaller, rural hospital. The prevalence of antibody also varied greatly within the high-risk groups; the highest prevalence of antibody was seen among surgical house officers (15%). The rate of acceptance of vaccine among hospitals ranged from 57.5% to 23.7%. Reasons for vaccine non-acceptance included fear of as yet unknown side effects, perceived low risk of hepatitis acquisition and possible effects on present or future pregnancies.

Our experience illustrates some of the epidemiologic and practical aspects that must be addressed in administering a hospital-based HBV vaccine program. Among the five hospitals, we saw marked inter- and intra-hospital variations in the prevalence of anti-HBs among high-risk employees. More significantly, we observed unexpectedly low rates of vaccine acceptance among high-risk personnel.

Potential hazards of puncture wounds have been well-defined and include transmission of hepatitis B virus, acquired immunodeficiency syndrome, syphilis, malaria, and other infectious diseases. Yet, standard methodology has not been used for statistical comparison. Attack rates have been expressed as needlesticks per full-time equivalents, needlesticks per employee per year, punctures per number of personnel, or punctures per number of hospital beds. These calculations do not account for the amount of time during which an employee is at risk of receiving a needle puncture. Also, numbers alone cannot account for intensity of care, potential exposures, or hours at risk. Nor can numbers provide an estimate of potential risk. A rate is more valuable than numbers because it measures the probability of occurrence. A meaningful incidence rate would be based on uniform data collection and would provide the number of puncture wounds per year for a standardized work period. This is similar in concept to nosocomial infections per patient-days of exposure. We propose the application of standard labor statistics methodology which accounts for man-hours worked, can be readily obtained in health care facilities, and can be modified as described here.

Neisseria meningitidis is an exclusive human pathogen. The organism was first recognized by Weichselbaum in 1887 in the spinal fluid of six patients with acute cerebrospinal meningitis. He called it Diplococcus intracellularis meningitidis because of the presence of the organism within leukocytes from the spinal fluid. Subsequent studies established the meningococcus as the cause of epidemic cerebrospinal fever and placed the organism in the genus Neisseria. Despite the availability of effective antimicrobials and partially effective vaccines, N. meningitidis remains one of the most frequent causes of rapidly fatal sepsis and meningitis.