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The ‘G’ men: a profile of GBL/GHB users in an area of high drug-related mortality

Published online by Cambridge University Press:  11 August 2014

S. Durgahee
Affiliation:
Substance Misuse Service, Sussex Partnership NHS Foundation Trust, Brighton, UK
G. Allen
Affiliation:
Substance Misuse Service, Sussex Partnership NHS Foundation Trust, Brighton, UK
H. Williams*
Affiliation:
Substance Misuse Service, Sussex Partnership NHS Foundation Trust, Brighton, UK Brighton and Sussex Medical School, University of Sussex, Falmer, UK
*
*Address for correspondence: H. Williams, Substance Misuse Service, Sussex Partnership NHS Foundation Trust, 26 Ditchling Road, Brighton BN1 4SF, UK. (Email: hugh.williams@sussexpartnership.nhs.uk)

Abstract

Objectives

Gamma-butyrolactone/gamma-hydroxybutyrate (GBL/GHB) and related analogues are increasingly misused. The study reports on patient characteristics, nature and pattern of use, complications and comorbidity for a cohort of patients presenting to a large Substance Misuse Service in Brighton and Hove City.

Method

A retrospective case-note review of routinely collected clinical data on patients with primary GBL/GHB misuse.

Results

In all, 24 individuals were male and 3 female, with a mean age of 34 years. A total of 21 males identified themselves as gay and 1 female as bisexual. Just over half (15, 56%), respectively, were living in stable accommodation and were in employment or third-level education. In all, 22 (81%) met criteria for physical dependence and two-thirds (18, 67%) had experienced overdose. The group was using large amounts of GBL (mean 53 ml/day) with a significant number (25, 93%) using ‘around the clock’ (every 1–3 hours). Over one-third (10, 37%) had a diagnosis of HIV and with 24 (89%) having a presumptive diagnosis of anxiety disorder.

Conclusions

A profile of gay men with relatively stable lifestyles, but nevertheless with a high rate of complication of GBL/GHB use and with a significant comorbidity (HIV and psychological problems) was identified. The need for integrated specialist services and the importance of liaison with Emergency Departments and HIV services is highlighted.

Type
Short Report
Copyright
© College of Psychiatrists of Ireland 2014 

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References

Beddoes, D, Sheikh, S, Khanna, M, Francis, R (2010). The Impact of Drugs on Different Minority Groups: LGBT Groups. UK Drug Policy Commission (UKDPC): London.Google Scholar
Bell, J, Collins, R (2011). Gamma-butyrolactone (GBL) dependence and withdrawal. Addiction 106, 442447.Google Scholar
Bowden-Jones, O (2013). ‘Legal highs’ and other ‘club drugs’: why the song and dance? The Psychiatrist 37, 185187.Google Scholar
Dargan, PI, Button, J, Davis, S, Ramsey, J, George, S, Holt, DW, Wood, DM (2009). The first reported UK fatality related to gamma-butyrolactone (GBL) ingestion. Journal of the Royal Society of Medicine 102, 545547.Google Scholar
Degenhardt, L, Darke, S, Dillon, P (2002). GHB use among Australians: characteristics, use patterns and associated harm. Drug and Alcohol Dependence 67, 8994.Google Scholar
Degenhardt, L, Darke, S, Dillon, P (2003). The prevalence and correlates of gamma-hydroxybutyrate (GHB) overdose among Australian users. Addiction 98, 199204.Google Scholar
Galloway, GP, Frederick-Osbourne, SL, Seymour, R, Contini, SE, Smith, DE (2000). Abuse and therapeutic potential of gamma-hydroxybutyric acid. Alcohol 20, 263269.Google Scholar
Gonzalez, A, Nutt, D (2005). Gamma-hydroxybutyrate abuse and dependency. Journal of Psychopharmacology 19, 195204.Google Scholar
Kirby, T, Thornber-Dunwell, M (2013). High risk drug practices tighten grip on London gay scene. Lancet 381, 101102.Google Scholar
Kroenke, K, Spitzer, RL, Williams, JB, Monahan, PO, Lowe, B (2007). Anxiety disorders in primary care: prevalence, impairment, comorbidity, and detection. Annals of Internal Medicine 146, 317325.Google Scholar
McDonough, M, Kennedy, N, Glasper, A, Bearn, J (2004). Clinical features and management of gamma-hydroxybutyrate (GHB) withdrawal: a review. Drug and Alcohol Dependence 75, 39.Google Scholar
Miotto, K, Darakjian, J, Basch, J, Murray, S, Zogg, J, Rawson, R (2001). Gamma-hydroxybutyric acid: patterns of use, effects and withdrawal. American Journal on Addictions 10, 232241.Google Scholar
National Treatment Agency for Substance Misuse (2012). Club Drugs: Emerging Trends and Risks. NTA: London.Google Scholar
Ryan, J, Stell, I (1997). Gamma-hydroxybutyrate – a coma inducing recreational drug. Journal of Accident and Emergency Medicine 14, 259261.Google Scholar
Williams, H, Taylor, R, Roberts, M (1998 a). Gamma-hydroxybutyrate (GHB): a new drug of misuse. Irish Medical Journal 91, 5657.Google ScholarPubMed
Williams, H, Dratcu, L, Taylor, R, Roberts, M, Oyefeso, A (1998 b). ‘Saturday night fever’: ecstasy related problems in a London accident and emergency department. Journal of Accident and Emergency Medicine 15, 322326.Google Scholar