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Influence of diet on plasma thyroxine response to thyroid stimulating hormone in growing lambs

Published online by Cambridge University Press:  27 March 2009

Patricia M. M. Godden
Affiliation:
Department of Agricultural Biochemistry and Nutrition, University of Newcastle upon Tyne, Newcastle upon Tyne NJE1 7RU
T. E. C. Weekes
Affiliation:
Department of Agricultural Biochemistry and Nutrition, University of Newcastle upon Tyne, Newcastle upon Tyne NJE1 7RU

Summary

In an initial experiment four mature sheep were injected with saline or 25, 75 or 150 m units bovine thyroid stimulating hormone (TSH)/kg live weight. All doses of TSH stimulated a similar release of thyroxine.

In a second experiment ten lambs were fed chopped dried grass from weaning until 108 days old (period 1). Five of the lambs (group 1) were then fed 30% barley: 70% grass until 178 days of age; the remaining lambs (group 2) continued to receive grass (period 2). After 178 days group 1 was fed 70% barley: 30% grass and group 2 30% barley: 70% grass (period 3). All lambs were injected with 25 m units TSH/kg live weight at 105–108 days of age, 174–178 days and 220–227 days. The thyroxine response to TSH was greatest in lambs fed 30% barley: 70% grass in periods 2 and 3. Plasma insulin and glucose concentrations tended to decrease after TSH.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1981

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