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Published online by Cambridge University Press:  14 May 2012

Department of Pediatrics, National Research Centre (NRC), Egypt
Department of Research on Children with Special Needs (NRC), Egypt
Department of Pediatrics, National Research Centre (NRC), Egypt
Departments of Environmental and Occupational Medicine (NRC), Egypt
Department of Genetic Medicine and Development, Geneva University Hospital, Switzerland
Department of Research on Children with Special Needs (NRC), Egypt


A total of 3961 married couples from six major geographical areas representing the South Sinai governorates in Egypt were studied to assess the rate of consanguineous marriage. The population of six selected areas (St Catherines, Nuweiba, Abu Rudeis, Ras Sudr, El Tor and Abu Zenima) were subdivided into Bedouin, urban and mixed populations. A questionnaire-based interview was conducted showing that the consanguinity rate in this region is 37.5%, with the highest rate recorded in Abu Rudeis (52.3%) and lowest rate in Nuweiba (24.1%). Consanguinity was significantly higher among the Bedouin population compared with the urban population in Abu Rudeis, Ras Sudr, El Tor and Abu Zenima, while in St Catherines and Nuweiba there was no statistically significant difference. Among consanguineous couples, 5%, 60% and 35% were double first cousins, first cousins and second cousins respectively. The mean inbreeding coefficient α of the studied population was 0.01845.

Research Article
Copyright © Cambridge University Press 2012

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