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The Use of Oestrogens for Postcoital Contraception

  • Ruth Coles (a1)

Summary

Oestrogens as postcoital contraception have been prescribed for 282 women at the Brook Advisory Centre (Avon) since January 1973. A daily dose of 50 mg diethylstilboestrol for 5 days started within 72 hr of unprotected intercourse was used from January 1973. This was changed to 5 mg ethinyl oestradiol in May 1974. There were no pregnancies nor any serious side effects. Follow-up showed that most women had their next period at the expected time.

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References

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Dodds, E.C., Goldberg, L., Sawson, W. & Robinson, R. (1938) Oestrogenic activity of certain synthetic compounds. Nature, Lond. 141, 247.
Haspels, A.A. (1970) Post-coital oestrogens in large doses. Sixth World Congress of Gynaecology and Obstetrics,New York,1970.
Inhoffen, H.H. & Hohlweg, W. (1938) Neue per os-wirksame weibliche Keimdrüsenhorrnon-Derivate: 17-Aethinyl-oestradiol und Pregnen-in-on-3-ol-17. Naturwissenschaften, 26, 96.
Kuchera, K.K. (1971) Post-coital contraception with diethylstilboestrol. J. Am. med. Ass. 218, 562.
Morris, J.M. & Van Wagenen, G. (1966) Compounds interfering with ovum implantation and development. III. The role of oestrogens. Am. J. Obstet. Gynec. 96, 804.
Parkes, A.S. & Bellerby, C.W. (1926) Studies on the internal secretions of the ovary. II. The effects of injection of the oestrus producing hormone during pregnancy.
Smith, M.G. (1926) On the interruption of pregnancy in the rat by the injection of ovarian follicular extract. Bull. Johns Hopkins Hosp. 39, 203.
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Journal of Biosocial Science
  • ISSN: 0021-9320
  • EISSN: 1469-7599
  • URL: /core/journals/journal-of-biosocial-science
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