Hostname: page-component-76fb5796d-qxdb6 Total loading time: 0 Render date: 2024-04-27T22:10:22.931Z Has data issue: false hasContentIssue false
  • English
  • Français

Concentrations of antimicrobial components in milk at dry off and postpartum and their relationships to new high somatic cell counts at quarter level in dairy cows

Published online by Cambridge University Press:  16 February 2024

Naoki Suzuki ,
Rika Harada ,
Yusaku Tsugami ,
Takahiro Nii  and
Naoki Isobe
Naoki Suzuki
Affiliation:
Graduate School of Integrated Sciences for Life, Hiroshima University, Higashi-Hiroshima, Hiroshima 7369-8528, Japan
Rika Harada
Affiliation:
Graduate School of Integrated Sciences for Life, Hiroshima University, Higashi-Hiroshima, Hiroshima 7369-8528, Japan
Yusaku Tsugami
Affiliation:
Graduate School of Integrated Sciences for Life, Hiroshima University, Higashi-Hiroshima, Hiroshima 7369-8528, Japan
Takahiro Nii
Affiliation:
Graduate School of Integrated Sciences for Life, Hiroshima University, Higashi-Hiroshima, Hiroshima 7369-8528, Japan
Naoki Isobe*
Affiliation:
Graduate School of Integrated Sciences for Life, Hiroshima University, Higashi-Hiroshima, Hiroshima 7369-8528, Japan
*
Corresponding author: Naoki Isobe; Email: niso@hiroshima-u.ac.jp
Get access Rights & Permissions [Opens in a new window]

Abstract

We investigated the antimicrobial components in cow milk at dry off and postpartum and their contribution in preventing new high SCC at quarter level. Milk samples from 72 quarters of 19 lactating cows were collected at last milking before dry off and at 7 d after parturition. Milk yield of each cow was recorded and SCC, IgG, IgA, lactoferrin, lingual antimicrobial peptide (LAP), and S100A7 concentrations in each quarter milk sample were measured. The postpartum milk yield was significantly higher than that at dry off. The IgG, IgA and lactoferrin concentrations in milk at dry off were significantly higher than those at postpartum, whereas the LAP concentration was lower. Quarters with SCC < 300 000 cells/ml at both dry off and postpartum were classified as persistent low SCC (PL) whereas those that rose above that same threshold postpartum were classified as new high SCC (NH). At dry off, IgG and LAP concentrations in milk were significantly higher in PL than in NH. These results suggest that high LAP concentrations during the dry period may contribute toward the prevention of new high SCC.

Keywords

Defensindry periodinnate immunitysomatic cell counts
Type
Research Article
Information
Journal of Dairy Research , First View , pp. 1 - 3
Copyright
Copyright © The Author(s), 2024. Published by Cambridge University Press on behalf of Hannah Dairy Research Foundation

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Cakebread, JA, Humphrey, R and Hodgkinson, AJ (2015) Immunoglobulin A in bovine milk: a potential functional food? Journal of Agricultural Food Chemistry 63, 7311–7316.CrossRefGoogle ScholarPubMed
Gurao, A, Kashyap, SK and Singh, R (2017) β-defensins: an innate defense for bovine mastitis. Veterinary World 10, 990–998.CrossRefGoogle ScholarPubMed
Hernández-Castellano, L, Wall, SK, Stephan, R, Corti, S and Bruckmaier, R (2017) Milk somatic cell count, lactate dehydrogenase activity, and immunoglobulin G concentration associated with mastitis caused by different pathogens: a field study. Schweizer Archiv für Tierheilkunde 159, 283–290.CrossRefGoogle ScholarPubMed
Isobe, N (2017) Control mechanisms for producing antimicrobial factors in ruminant mammary gland. Animal Science Journal 88, 937–943.CrossRefGoogle ScholarPubMed
Isobe, N, Hosoda, K and Yoshimura, Y (2009a) Immunolocalization of lingual antimicrobial peptide (LAP) in the bovine mammary gland. Animal Science Journal 80, 446–450.CrossRefGoogle ScholarPubMed
Isobe, N, Nakamura, J, Nakano, H and Yoshimura, Y (2009b) Existence of functional lingual antimicrobial peptide in bovine milk. Journal of Dairy Science 92, 2691–2695.CrossRefGoogle ScholarPubMed
Kawai, K, Shimazaki, K, Higuchi, H and Nagahata, H (2007) Antibacterial activity of bovine lactoferrin hydrolysate against mastitis pathogens and its effect on superoxide production of bovine neutrophils. Zoonoses and Public Health 54, 160–164.CrossRefGoogle ScholarPubMed
Khatun, M, Bruckmaier, RM, Thomson, PC, House, J and García, SC (2019) Suitability of somatic cell count, electrical conductivity, and lactate dehydrogenase activity in foremilk before vs. after alveolar milk ejection for mastitis detection. Journal of Dairy Science 102, 9200–9212.CrossRefGoogle ScholarPubMed
Krattley-Roodenburg, B, Huybens, LJ, Nielen, M and van Werven, T (2021) Dry period management and new high somatic cell count during the dry period in Dutch dairy herds under selective dry cow therapy. Journal of Dairy Science 104, 6975–6984.CrossRefGoogle ScholarPubMed
McMullen, CK, Sargeant, JM, Kelton, DF, Churchill, KJ, Cousins, KS and Winder, CB (2021) Modifiable management practices to improve udder health in dairy cattle during the dry period and early lactation: a scoping review. Journal of Dairy Science 104, 10143–10157.CrossRefGoogle ScholarPubMed
Pallister, KB, Mason, S, Nygaard, TK, Liu, B, Griffith, S, Jones, J, Linderman, S, Hughes, M, Erickson, D, Voyich, JM, Davis, MF and Wilson, E (2015) Bovine CCL28 mediates chemotaxis via CCR10 and demonstrates direct antimicrobial activity against mastitis causing bacteria. PLoS One 10, e0138084.CrossRefGoogle ScholarPubMed
Vilar, MJ and Rajala-Schultz, PJ (2020) Dry-off and dairy cow udder health and welfare: effects of different milk cessation methods. Veterinary Journal 262, 105503.CrossRefGoogle ScholarPubMed
Zhang, GW, Lai, SJ, Yoshimura, Y and Isobe, N (2014) Messenger RNA expression and immunolocalization of psoriasin in the goat mammary gland and its milk concentration after an intramammary infusion of lipopolysaccharide. Veterinary Journal 202, 89–93.CrossRefGoogle ScholarPubMed
Zhao, S, Zhang, C, Wang, J, Bu, D, Liu, G and Zhou, L (2010) Association of production factors with milk IgA and IgM concentrations in normal lactating cows. Journal of Dairy Research 77, 481–486.CrossRefGoogle ScholarPubMed
Supplementary material: File

Suzuki et al. supplementary material

Suzuki et al. supplementary material
Download Suzuki et al. supplementary material(File)
File 348.5 KB