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Effect of propylene glycol supplementation around parturition on milk yield, reproduction performance and some hormonal and metabolic characteristics in dairy cows

Published online by Cambridge University Press:  01 June 2009

Andrea Formigoni ,
Marie-Christine Cornil ,
Alberto Prandi ,
Archimede Mordenti ,
Andriana Rossi ,
Daniel Portetelle  and
Robert Renaville
Andrea Formigoni
Affiliation:
Facoltà di Medicina Veterinaria, Istituto di Zootecnia e Nutrizione Animate, Università degli Studi di Bologna, I-40064 Ozzano Emilia (Bologna), Italia
Marie-Christine Cornil
Affiliation:
Département de Biologie Moléculaire et de Physiologie Animate, Faculté des Sciences Agronomiques, Avenue Maréchal Juin 13, B-5030 Gembloux, Belgique
Alberto Prandi
Affiliation:
Dipartimento di Scienze degli Alimenti, Università degli Studi di Undine, I-33010 Pagnacco (Undine), Italia
Archimede Mordenti
Affiliation:
Facoltà di Medicina Veterinaria, Istituto di Zootecnia e Nutrizione Animate, Università degli Studi di Bologna, I-40064 Ozzano Emilia (Bologna), Italia
Andriana Rossi
Affiliation:
Dipartimento di Scienze degli Alimenti, Università degli Studi di Undine, I-33010 Pagnacco (Undine), Italia
Daniel Portetelle
Affiliation:
Département de Microbiologie, Faculté des Sciences Agronomiques, Avenue Maréchal Juin 6, B-5030 Gembloux, Belgique
Robert Renaville
Affiliation:
Département de Biologie Moléculaire et de Physiologie Animate, Faculté des Sciences Agronomiques, Avenue Maréchal Juin 13, B-5030 Gembloux, Belgique
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Summary

Thirty-nine multiparous Holstein cows were used to measure the effect of propylene glycol treatment around parturition on milk yield, reproductive efficiency and some hormone and metabolite concentrations. Cows were assigned randomly to control (n = 19) or propylene glycol treated (n = 20) groups. Propylene glycol (300g) was administered directly mixed with the diet from day 10 prior to the expected calving date until parturition (day 0) and orally after dilution in 1 l water on days 3, 6, 9 and 12. Blood samples were collected on days −20, −5, 0, 3, 10, 25 and 50 while milk samples were taken weekly until 13 weeks post partum. Body condition scores, recorded on days −20, 15 and 50, were not affected by propylene glycol administration. Propylene glycol did not significantly affect milk yield or composition but linear somatic cell score measured from the first 13 weeks post partum was reduced by propylene glycol administration (P < 0·01). Moreover, propylene glycol reduced milk urea (−25 mg/l, P < 0·05), especially during the first 9 weeks post partum. Plasma insulin concentrations were similar in both groups during the experiment while insulin-like growth factor I (P < 0·05) and insulin-like growth factor-binding protein 3 (P < 0·001) levels were higher on days 10, 25 and 50 post partum in the propylene glycol group. Propylene glycol administration decreased plasma non-esterified fatty acid concentrations (P < 0·05 to P < 0·01) but increased total cholesterol levels (P < 0·01) after parturition while 3-hydroxy-butyrate levels were unaffected by the treatment. Changes in the hormone and metabolic concentrations after propylene glycol administration in the last few days of gestation and the first week of lactation seem to indicate that energy balance in the treated group was probably more positive than in the control group. There was also evidence that propylene glycol administration prevented fatty liver syndrome and hastened the resumption of oestrous cycles (P < 0·001).

Type
Original Articles
Information
Journal of Dairy Research , Volume 63 , Issue 1 , February 1996 , pp. 11 - 24
Copyright
Copyright © Proprietors of Journal of Dairy Research 1996

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