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Metabolism of the lactating cow: I. Animal elements of a mechanistic model

Published online by Cambridge University Press:  01 June 2009

R. Lee Baldwin ,
James France  and
Margaret Gill
R. Lee Baldwin
Affiliation:
Department of Animal Science, University of California, Davis, CA 95616, USA
James France
Affiliation:
Animal and Grassland Research Institute, Hurley, Maidenhead SL6 5LR, UK
Margaret Gill
Affiliation:
Animal and Grassland Research Institute, Hurley, Maidenhead SL6 5LR, UK
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Summary

A mechanistic model of dairy cow metabolism is described. The model was constructed as part of a programme directed toward quantitative and dynamic analysis of concepts and data regarding factors which influence the partition of nutrients in lactating dairy cows. Sensitivity and behavioural analyses undertaken using the model indicate that concepts and data arising from tissue level experiments conducted in vitro can be used to structure and parameterize whole-animal models since the quantitative and dynamic behaviour of such a model is acceptable. These analyses indicate further that such models can be used to evaluate factors which influence patterns of nutrient utilization. By way of illustrating the model's utility regarding evaluation of concepts relating to the interpretation of energy balance experiments, results of a simulated energy balance experiment are presented. Apparent costs of milk synthesis are partitioned among biosynthetic costs, physiological costs, ion transport costs and the reductions in energy expenditures in synthesis of body components which accompany increasingly negative energy balances due to feed restriction.

Type
Original Articles
Information
Journal of Dairy Research , Volume 54 , Issue 1 , February 1987 , pp. 77 - 105
Copyright
Copyright © Proprietors of Journal of Dairy Research 1987

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References

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