Skip to main content Accessibility help
×
Home

The establishment of DOHaD working groups in Australia and New Zealand

  • S. L. Prescott (a1), K. Allen (a2), K. Armstrong (a3), C. Collins (a4), H. Dickinson (a5), K. Gardiner (a6), F. Jacka (a7), C. Jasoni (a8), T. Moore (a8), K. M. Moritz (a9), B. Muhlhausler (a10) (a11), W. Siero (a6), K. Sim (a12), R. Nanan (a12), R. Saffery (a13), G. Singh (a14) (a15), M. H Vickers (a16) and J. M. Craig (a6)...

Abstract

The evidence underpinning the developmental origins of health and disease (DOHaD) is overwhelming. As the emphasis shifts more towards interventions and the translational strategies for disease prevention, it is important to capitalize on collaboration and knowledge sharing to maximize opportunities for discovery and replication. DOHaD meetings are facilitating this interaction. However, strategies to perpetuate focussed discussions and collaborations around and between conferences are more likely to facilitate the development of DOHaD research. For this reason, the DOHaD Society of Australia and New Zealand (DOHaD ANZ) has initiated themed Working Groups, which convened at the 2014–2015 conferences. This report introduces the DOHaD ANZ Working Groups and summarizes their plans and activities. One of the first Working Groups to form was the ActEarly birth cohort group, which is moving towards more translational goals. Reflecting growing emphasis on the impact of early life biodiversity – even before birth – we also have a Working Group titled Infection, inflammation and the microbiome. We have several Working Groups exploring other major non-cancerous disease outcomes over the lifespan, including Brain, behaviour and development and Obesity, cardiovascular and metabolic health. The Epigenetics and Animal Models Working Groups cut across all these areas and seeks to ensure interaction between researchers. Finally, we have a group focussed on ‘Translation, policy and communication’ which focusses on how we can best take the evidence we produce into the community to effect change. By coordinating and perpetuating DOHaD discussions in this way we aim to enhance DOHaD research in our region.

Copyright

Corresponding author

*Address for correspondence: J. M Craig, Murdoch Childrens Research Institute, RCH, Flemington Road, Parkville, Melbourne, VIC 3052, Australia. (Email jeff.craig@mcri.edu.au)

References

Hide All
1. Griffith, L, van den Heuvel, E, Fortier, I, et al. Harmonization of Cognitive Measures in Individual Participant Data and Aggregate Data Meta-Analysis. 2013. Agency for Healthcare Research and Quality (US): Rockville, MD.
2. Caballero, S, Pamer, EG. Microbiota-mediated inflammation and antimicrobial defense in the intestine. Annu Rev Immunol. 2015; 33, 227256.
3. Kamada, N, Seo, SU, Chen, GY, Nunez, G. Role of the gut microbiota in immunity and inflammatory disease. Nat Rev Immunol. 2013; 13, 321335.
4. McKenney, PT, Pamer, EG. From hype to hope: the gut microbiota in enteric infectious disease. Cell. 2015; 163, 13261332.
5. Hsu, P, Nanan, R. Foetal immune programming: hormones, cytokines, microbes and regulatory T cells. J Reprod Immunol. 2014; 104–105, 27.
6. Gluckman, PD. epigenetics and metabolism in 2011: epigenetics, the life-course and metabolic disease. Nat Rev Endocrinol. 2012; 8, 7476.
7. Shah, S, McRae, AF, Marioni, RE, et al. Genetic and environmental exposures constrain epigenetic drift over the human life course. Genome Res. 2014; 24, 17251733.
8. International Association of Diabetes in Pregnancy Study Group Working Group on Outcome D, Feig, DS, Corcoy, R, et al. Diabetes in pregnancy outcomes: a systematic review and proposed codification of definitions. Diabetes Metab Res Rev. 2015; 31, 680690.

Keywords

Type Description Title
WORD
Supplementary materials

Prescott supplementary material
Table S1

 Word (27 KB)
27 KB

Metrics

Altmetric attention score

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed